Prevalence of hepatitis B, C, and delta virus infections among children in Mongolia: Progress in childhood immunization

Mongolia is highly endemic for hepatitis B virus (HBV), hepatitis C virus (HCV), and hepatitis delta virus (HDV) infections among apparently healthy adults. However, the age‐specific prevalence of ongoing HBV, HCV, and HDV infections among children in Mongolia remains unknown. Therefore, samples obt...

Full description

Saved in:
Bibliographic Details
Published in:Journal of medical virology 2007-08, Vol.79 (8), p.1064-1074
Main Authors: Tsatsralt-Od, Bira, Takahashi, Masaharu, Endo, Kazunori, Agiimaa, Dondog, Buyankhuu, Osorjin, Ninomiya, Masashi, Lorenzo, Felipe R., Okamoto, Hiroaki
Format: Article
Language:English
Subjects:
Adolescent
Biological and medical sciences
Child
Child, Preschool
children
Epidemiology
Female
Fundamental and applied biological sciences. Psychology
Genotype
Hepatitis B - epidemiology
Hepatitis B - prevention & control
Hepatitis B virus
Hepatitis B virus - genetics
Hepatitis C - epidemiology
Hepatitis C - prevention & control
Hepatitis C virus
Hepatitis D - epidemiology
Hepatitis D - prevention & control
Hepatitis D virus
Hepatitis Delta Virus
Humans
immunization
Immunization Programs
Infant
Male
Microbiology
Molecular Sequence Data
Mongolia
Mongolia - epidemiology
Phylogeny
Population Surveillance
Prevalence
Risk Factors
Viral Hepatitis Vaccines - administration & dosage
Viral Hepatitis Vaccines - immunology
Virology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Mongolia is highly endemic for hepatitis B virus (HBV), hepatitis C virus (HCV), and hepatitis delta virus (HDV) infections among apparently healthy adults. However, the age‐specific prevalence of ongoing HBV, HCV, and HDV infections among children in Mongolia remains unknown. Therefore, samples obtained from a total of 655 apparently healthy children of 0.3–15 years of age (307 boys and 348 girls; age, mean ± standard deviation [SD], 8.4 ± 4.2 years) living in Mongolia, between October 2005 and January 2006, were tested for serological and molecular markers of HBV, HCV, and HDV infections. Although 88.7% of the 655 children studied were immunized against hepatitis B, 64 (9.8%) tested positive for hepatitis B surface antigen (HBsAg) and/or HBV DNA and 13 (2.0%) for HDV RNA. Twenty‐seven children (4.1%) had detectable HCV RNA. Collectively, 82 (12.5%) were viremic for one or more of these viruses, including eight children with dual viremia of HBV/HCV and one child with triple HBV/HCV/HDV viremia. When children without anti‐HBc, anti‐HCV and anti‐HDV IgG (n = 510) served as a control, a history of hospitalization was significantly associated with HBV viremia (P 
ISSN:0146-6615
1096-9071
DOI:10.1002/jmv.20867