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Acute Disseminated Encephalomyelitis Following Infectious Mononucleosis

Two months following an Epstein-Barr virus infection, a 17-year-old white female presented with seizures, intermittent visual changes, and altered mental status. Magnetic resonance imaging showed white matter changes of acute disseminated encephalomyelitis with a predilection for posterior cerebral...

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Bibliographic Details
Published in:Journal of child neurology 2007-03, Vol.22 (3), p.324-328
Main Authors: Bahadori, Hamid R., Williams, Virginia C., Turner, Robert P., Rumboldt, Zoran, Reigart, J. Routt, Fowler, Sandra L., Chavis, Pamela S., Maria, Bernard L.
Format: Article
Language:English
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Summary:Two months following an Epstein-Barr virus infection, a 17-year-old white female presented with seizures, intermittent visual changes, and altered mental status. Magnetic resonance imaging showed white matter changes of acute disseminated encephalomyelitis with a predilection for posterior cerebral artery distributions but without radiological evidence of arteritis. Epstein-Barr virus titers and polymerase chain reaction analysis results for the virus were consistent with postinfectious acute disseminated encephalomyelitis. The symptoms and signs improved following treatment with high-dose corticosteroids and intravenous immunoglobulin. Although Epstein-Barr virus can cause acute viral encephalomyelitis, the authors report a case of acute disseminated encephalomyelitis months after acute Epstein-Barr virus infection.
ISSN:0883-0738
1708-8283
DOI:10.1177/0883073807300534