A Study of Remote Memory Impairment in Alzheimer’s Disease by Using the Family Line Test

We evaluated remote autobiographical memory impairment in 25 patients with probable Alzheimer’s disease (AD) and 25 sex-, age- and education-matched healthy subjects by using a newly developed, highly effective assessment tool for remote memory, the Family Line Test (FLT). The FLT yields a total sco...

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Bibliographic Details
Published in:Dementia and geriatric cognitive disorders 2000-01, Vol.11 (1), p.53-58
Main Authors: Kazui, Hiroaki, Hashimoto, Mamoru, Hirono, Nobutsugu, Imamura, Toru, Tanimukai, Satoshi, Hanihara, Tokiji, Ikeda, Manabu, Komori, Kenjiro, Ikejiri, Yoshitaka, Mori, Etsuro
Format: Article
Language:English
Subjects:
Aged
Alzheimer Disease - diagnosis
Alzheimer Disease - psychology
Biological and medical sciences
Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
Female
Humans
Life Change Events
Male
Medical sciences
Mental Recall
Middle Aged
Neurology
Neuropsychological Tests - statistics & numerical data
Original Research Article
Psychometrics
Reference Values
Reproducibility of Results
Retention (Psychology)
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Summary:We evaluated remote autobiographical memory impairment in 25 patients with probable Alzheimer’s disease (AD) and 25 sex-, age- and education-matched healthy subjects by using a newly developed, highly effective assessment tool for remote memory, the Family Line Test (FLT). The FLT yields a total score, scores for 3 lifetime periods and the duration of remote memory impairment. In the patients with AD, the total score was significantly lower and the duration of remote memory impairment was significantly longer than in the healthy controls. A prominent temporal gradient in remote memory impairment was documented in the patients with AD. The total FLT score and duration of remote memory impairment correlated with recent memory and general cognitive dysfunctions.
ISSN:1420-8008
1421-9824
DOI:10.1159/000017214