Adrenal Insufficiency in Critically Ill Emergency Department Patients: A Taiwan Preliminary Study

Objective: Unrecognized adrenal insufficiency can have serious consequences in critically ill emergency department (ED) patients. This prospective pilot study of adrenal function in patients with severe illness was undertaken to determine the prevalence of adrenal dysfunction and any relation to pri...

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Bibliographic Details
Published in:Academic emergency medicine 2001-07, Vol.8 (7), p.761-764
Main Authors: Chang, Shy‐Shin, Liaw, Shiumn‐Jen, Bullard, Michael J., Chiu, Te‐Fa, Chen, Jih‐Chang, Liao, How‐Chin
Format: Article
Language:English
Subjects:
Adrenal Insufficiency - blood
Adrenal Insufficiency - complications
Adrenal Insufficiency - diagnosis
Adrenal Insufficiency - epidemiology
Adrenal Insufficiency - therapy
Aged
cortisol
Critical Illness
Drugs, Chinese Herbal - adverse effects
Emergency Service, Hospital - statistics & numerical data
Emergency Treatment - methods
Female
Humans
Hydrocortisone - blood
hypofunction, adrenal gland
Male
medicine, herbal
Middle Aged
myocardial infarction
Myocardial Infarction - complications
Pilot Projects
Prevalence
Prospective Studies
Sepsis - complications
sepsis syndrome
Taiwan - epidemiology
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Summary:Objective: Unrecognized adrenal insufficiency can have serious consequences in critically ill emergency department (ED) patients. This prospective pilot study of adrenal function in patients with severe illness was undertaken to determine the prevalence of adrenal dysfunction and any relation to prior herbal drug use. Methods: In a high‐volume urban tertiary care ED, adult patients with sepsis or acute myocardial infarction (AMI) were eligible for the study. Over a two‐month period, a convenience sample was enrolled by the authors on arrival to the ED. Inclusion criteria were systemic inflammatory response syndrome (SIRS) criteria plus evidence of at least one organ dysfunction or cardiac marker plus electrocardiogram‐proven AMI. Exclusion criteria included known corticosteroid use. Serum cortisol was measured on arrival and for those patients with a level of
ISSN:1069-6563
1553-2712
DOI:10.1111/j.1553-2712.2001.tb00202.x