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How Echinococcus granulosus Deals with Complement
Here, Ana Marı́a Ferreira and colleagues discuss the interplay between the larval stages of Echinococcus granulosus and an important effector arm of immunity: the host complement system. During early infection, the parasite activates complement, and hence complement-dependent inflammatory responses....
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| Published in: | Parasitology today (Regular ed.) 2000-04, Vol.16 (4), p.168-172 |
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| Main Authors: | , , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c421t-d1bad08a985248950c709bb94bb059eb92282190c09186c5bdbdda666142b74b3 |
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| cites | cdi_FETCH-LOGICAL-c421t-d1bad08a985248950c709bb94bb059eb92282190c09186c5bdbdda666142b74b3 |
| container_end_page | 172 |
| container_issue | 4 |
| container_start_page | 168 |
| container_title | Parasitology today (Regular ed.) |
| container_volume | 16 |
| creator | Ferreira, A.M. Irigoı́n, F. Breijo, M. Sim, R.B. Dı́az, A. |
| description | Here, Ana Marı́a Ferreira and colleagues discuss the interplay between the larval stages of
Echinococcus granulosus and an important effector arm of immunity: the host complement system. During early infection, the parasite activates complement, and hence complement-dependent inflammatory responses. However, on differentiation into the hydatid cyst, the parasite exposes to the host a structure – the cyst wall – that does not activate complement strongly. Mechanisms inhibiting complement activation on the cyst wall have been elucidated, contributing to the understanding of how this large, persistent, tissue-dwelling pathogen controls the inflammatory response. |
| doi_str_mv | 10.1016/S0169-4758(99)01625-7 |
| format | article |
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Echinococcus granulosus and an important effector arm of immunity: the host complement system. During early infection, the parasite activates complement, and hence complement-dependent inflammatory responses. However, on differentiation into the hydatid cyst, the parasite exposes to the host a structure – the cyst wall – that does not activate complement strongly. 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| ispartof | Parasitology today (Regular ed.), 2000-04, Vol.16 (4), p.168-172 |
| issn | 0169-4758 1873-1473 |
| language | eng |
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| source | ScienceDirect Freedom Collection |
| subjects | Animals Biological and medical sciences Cattle Complement Complement Activation Echinococcosis - immunology Echinococcus Echinococcus - growth & development Echinococcus - immunology Echinococcus granulosus Fundamental and applied biological sciences. Psychology Host-Parasite Interactions - immunology Hydatid disease Immune invasion Inflammation Life cycle. Host-agent relationship. Pathogenesis Mice Protozoa |
| title | How Echinococcus granulosus Deals with Complement |
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