Early predictors of mortality in penetrating compared with closed brain injury

Although brain injury incidence rates have been decreasing, the proportion of these injuries which are penetrating has been increasing. This study compares mortality amongst persons with penetrating and closed brain injuries and explores the relationship of early predictors of mortality. The study i...

Full description

Saved in:
Bibliographic Details
Published in:Brain injury 2001-09, Vol.15 (9), p.801-810
Main Authors: PEEK-ASA, Corinne, MCARTHUR, David, HOVDA, David, KRAUS, Jess
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Biological and medical sciences
Cohort Studies
Female
Head Injuries, Closed - mortality
Head Injuries, Closed - pathology
Head Injuries, Penetrating - mortality
Head Injuries, Penetrating - pathology
Humans
Injuries of the nervous system and the skull. Diseases due to physical agents
Male
Medical sciences
Middle Aged
Patient Care Planning
Prognosis
Regression Analysis
Retrospective Studies
Risk Factors
Survival Analysis
Traumas. Diseases due to physical agents
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Although brain injury incidence rates have been decreasing, the proportion of these injuries which are penetrating has been increasing. This study compares mortality amongst persons with penetrating and closed brain injuries and explores the relationship of early predictors of mortality. The study included 795 moderately or severely brain injured individuals identified through the UCLA Brain Injury Research Centre. Logistic regression was used to predict mortality by GCS level and brain injury type, controlling for age, gender, and presence of multiple trauma. Of the 795 individuals, 110 had penetrating and 685 had closed brain injury. Case fatality rates were higher for penetrating than closed injuries for all GCS, gender, age, and cause of injury categories. When controlling for GCS level at admission, age, gender, and multiple trauma, those with penetrating injuries were 6.6 (95% CI = 3.9-11.1) times more likely to die. As the pool of information about survival and recovery from penetrating injuries grows, decisions regarding clinical care and prevention activities can be more appropriately focused.
ISSN:0269-9052
1362-301X
DOI:10.1080/02699050010025768