Methods for assessing responsiveness: a critical review and recommendations

A review of the literature suggests there are two major aspects of responsiveness. We define the first as “internal responsiveness,” which characterizes the ability of a measure to change over a prespecified time frame, and the second as “external responsiveness,” which reflects the extent to which...

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Bibliographic Details
Published in:Journal of clinical epidemiology 2000-05, Vol.53 (5), p.459-468
Main Authors: Husted, Janice A., Cook, Richard J., Farewell, Vern T., Gladman, Dafna D.
Format: Article
Language:English
Subjects:
Arthritis, Psoriatic - drug therapy
Arthritis, Psoriatic - epidemiology
Biological and medical sciences
Clinical trials
Clinical Trials as Topic - statistics & numerical data
Data Interpretation, Statistical
Epidemiology
Female
General aspects
Humans
Male
Medical sciences
Methodology
Models, Statistical
Ontario - epidemiology
Outcome Assessment (Health Care) - statistics & numerical data
Outcome measures
Public health. Hygiene
Public health. Hygiene-occupational medicine
Regression Analysis
Responsiveness
Responsiveness statistics
Time Factors
Citations: Items that cite this one
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Summary:A review of the literature suggests there are two major aspects of responsiveness. We define the first as “internal responsiveness,” which characterizes the ability of a measure to change over a prespecified time frame, and the second as “external responsiveness,” which reflects the extent to which change in a measure relates to corresponding change in a reference measure of clinical or health status. The properties and interpretation of commonly used internal and external responsiveness statistics are examined. It is from the interpretation point of view that external responsiveness statistics are considered particularly attractive. The usefulness of regression models for assessing external responsiveness is also highlighted.
ISSN:0895-4356
1878-5921
DOI:10.1016/S0895-4356(99)00206-1