Individual reactivity and physiology of the stress response

The biological response to stress involves the activation of two main neuroendocrine components, the hypothalamic-pituitary-adrenal axis and the sympathoadrenal medullary systems. Looking at the responses to stressors in a laboratory setting, e.g., cortisol production after exercising on a treadmill...

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Bibliographic Details
Published in:Biomedicine & pharmacotherapy 2000-04, Vol.54 (3), p.122-128
Main Authors: Negrão, A.B., Deuster, P.A., Gold, P.W., Singh, A., Chrousos, G.P.
Format: Article
Language:English
Subjects:
catecholamines
cortisol
Exercise - physiology
exercise test
Hemodynamics - physiology
Hormones - blood
Humans
Stress, Physiological - physiopathology
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Summary:The biological response to stress involves the activation of two main neuroendocrine components, the hypothalamic-pituitary-adrenal axis and the sympathoadrenal medullary systems. Looking at the responses to stressors in a laboratory setting, e.g., cortisol production after exercising on a treadmill, is a valid and controlled way to study how people react to psychological and physical stressors. A common finding in such studies is that individuals respond bimodally to stress. More recently, researchers have been interested in the possible reasons why healthy individuals exhibit differential reactivity to stressors. The literature on the neuroendocrine responses to stress, with a particular focus on investigations of individual reactivity to psychological and physical stressors, is reviewed.
ISSN:0753-3322
1950-6007
DOI:10.1016/S0753-3322(00)89044-7