A New Anatomical Landmark for Reliable Identification of Human Area V5/MT: a Quantitative Analysis of Sulcal Patterning

The location of human area V5 (or MT) has been correlated with the intersection of the ascending limb of the inferior temporal sulcus (ALITS) and the lateral occipital sulcus (LO). This study was undertaken to attempt a replication and quantification of these observations using functional magnetic r...

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Bibliographic Details
Published in:Cerebral cortex (New York, N.Y. 1991) N.Y. 1991), 2000-05, Vol.10 (5), p.454-463
Main Authors: Dumoulin, Serge O., Bittar, Richard G., Kabani, Noor J., Baker, Curtis L., Le Goualher, Georges, Pike, G. Bruce, Evans, Alan C.
Format: Article
Language:English
Subjects:
Adult
Anatomy - standards
Female
Humans
Magnetic Resonance Imaging
Male
Parietal Lobe - anatomy & histology
Parietal Lobe - physiology
Photic Stimulation
Reproducibility of Results
Temporal Lobe - anatomy & histology
Temporal Lobe - physiology
Visual Cortex - anatomy & histology
Visual Cortex - physiology
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Summary:The location of human area V5 (or MT) has been correlated with the intersection of the ascending limb of the inferior temporal sulcus (ALITS) and the lateral occipital sulcus (LO). This study was undertaken to attempt a replication and quantification of these observations using functional magnetic resonance imaging. V5 was significantly activated in 19 hemispheres with alternating, low contrast, random checkerboard patterns. We confirmed the stereotaxic location of V5 and were able to describe a fairly consistent sulcal pattern in the parieto-temporo-occipital cortex. V5 was usually (95%) buried within a sulcus, most commonly within the inferior temporal sulcus (ITS) (11%), the ascending limb of the ITS (ALITS) (53%) and the posterior continuation of the ITS (26%). The average distance from V5 of two identified anatomical landmarks of V5, the junctions of the LO and the ALITS, and the ITS and ALITS, were both ~1 cm. However, the LO–ALITS junction often had to be determined by interpolation (47%), and was not always present even with interpolation (21%). In contrast, the ITS–ALITS junction was always present and V5 was usually (90%) located in a sulcus intersecting with this junction, making it a more reliable landmark for localizing V5 with respect to gross morphological features on individual cortical surfaces.
ISSN:1047-3211
1460-2199
1460-2199
DOI:10.1093/cercor/10.5.454