Enhanced Urinalysis Improves Identification of Febrile Infants Ages 60 Days and Younger at Low Risk for Serious Bacterial Illness

Investigators have sought to establish "low-risk" criteria to identify febrile young infants who can be observed safely without antibiotics. Previous studies have used criteria for standard urinalysis to identify suspected urinary tract infection; however, cases of urinary tract infection...

Full description

Saved in:
Bibliographic Details
Published in:Pediatrics (Evanston) 2001-10, Vol.108 (4), p.866-871
Main Authors: Herr, Sandra M, Wald, Ellen R, Pitetti, Raymond D, Choi, Sylvia S
Format: Article
Language:English
Subjects:
Age Factors
Analysis
Anti-Bacterial Agents - therapeutic use
Babies
Bacteremia - diagnosis
Bacteremia - epidemiology
Bacteremia - urine
Bacterial Infections - diagnosis
Bacterial Infections - epidemiology
Bacterial Infections - urine
Biological and medical sciences
Children
Diagnosis
Diseases
Female
Fever - diagnosis
Fever - drug therapy
Fever - urine
Humans
Infant
Infant, Newborn
Investigative techniques, diagnostic techniques (general aspects)
Male
Medical sciences
Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques
Pediatric diseases
Pediatrics
Risk Factors
Urinalysis
Urinalysis - methods
Urinary system
Urinary tract infections
Urinary Tract Infections - diagnosis
Urinary Tract Infections - epidemiology
Urinary Tract Infections - urine
Urinary tract infections in children
Urine
Urine - microbiology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Investigators have sought to establish "low-risk" criteria to identify febrile young infants who can be observed safely without antibiotics. Previous studies have used criteria for standard urinalysis to identify suspected urinary tract infection; however, cases of urinary tract infection have been missed. Enhanced urinalysis, using hemocytometer cell count and Gram stain performed on uncentrifuged urine, has been shown to have greater sensitivity and negative predictive value than standard urinalysis. The objective of this study was to evaluate the ability of criteria that incorporate enhanced urinalysis to identify febrile young infants who are at low risk for serious bacterial illness (SBI). Institutional guidelines were established in 1999 to evaluate in a retrospective cohort study infants who were /=38.0 degrees C. "Low-risk" criteria included 1) well appearance without focal infection (excluding otitis media); 2) no history of prematurity, illness, or previous antibiotics; 3) peripheral white blood cell count (WBC) between 5 and 15 000/mm(3); 4) absolute band count
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.108.4.866