Triple-dose contrast-enhanced images in neurologically symptomatic HIV-positive patients

Our purpose was to determine whether triple-dose delayed contrast-enhanced images would improve lesion detection in patients with symptomatic human immunodeficiency virus (HIV) infection. We reviewed 33 MRI studies on 29 patients. Single-dose immediate T1-weighted spin-echo (1x-T1) images were compa...

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Bibliographic Details
Published in:Neuroradiology 2000-04, Vol.42 (4), p.256-260
Main Authors: DIAZ-MARCHAN, P. J, HUANG, M. L, JACKSON, E. F, NORTON, R. E, HAYMAN, L. A
Format: Article
Language:English
Subjects:
Adult
AIDS/HIV
Biological and medical sciences
Brain - pathology
Brain Diseases - diagnosis
Brain Diseases - etiology
Brain Diseases - virology
Contrast Media - administration & dosage
Diagnosis, Differential
Drug Administration Schedule
Female
HIV Infections - complications
Human viral diseases
Humans
Infectious diseases
Magnetic Resonance Imaging - methods
Male
Medical sciences
Meninges - pathology
Middle Aged
Prospective Studies
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
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Summary:Our purpose was to determine whether triple-dose delayed contrast-enhanced images would improve lesion detection in patients with symptomatic human immunodeficiency virus (HIV) infection. We reviewed 33 MRI studies on 29 patients. Single-dose immediate T1-weighted spin-echo (1x-T1) images were compared with delayed triple-dose images (D3x-T1). Two neuroradiologists decided which technique showed more lesions, increased lesion conspicuity and/or altered the radiologic diagnosis. The D3x-T1 technique improved lesion detection in 14 of 29 patients (48%). In two patients (7%), the improvement changed the radiologic diagnosis by showing new meningeal lesions.
ISSN:0028-3940
1432-1920
DOI:10.1007/s002340050881