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Association between depression and worse disease-specific functional status in outpatients with coronary artery disease
Background The objective of this study was to determine if depression is associated with worse disease-specific functional status in patients with coronary artery disease. The study was designed as a cross-sectional survey and 3-month longitudinal cohort. Methods and Results The study took place in...
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| Published in: | The American heart journal 2000-07, Vol.140 (1), p.105-110 |
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| creator | Spertus, John A. McDonell, Mary Woodman, Catherine L. Fihn, Stephan D. |
| description | Background The objective of this study was to determine if depression is associated with worse disease-specific functional status in patients with coronary artery disease. The study was designed as a cross-sectional survey and 3-month longitudinal cohort. Methods and Results The study took place in outpatient clinics of 3 Veterans Administration hospitals. All 7282 enrollees were surveyed and 4560 (62.6%) returned baseline questionnaires, including a screening instrument for depression. Thirty-nine percent (n = 1793) reported evidence of coronary artery disease and 1282 patients (71.5%) returned the Seattle Angina Questionnaire; 1025 patients (80%) completed a subsequent 3-month series of instruments. Main outcome measures used were the Seattle Angina Questionnaire, a valid, reliable, and responsive disease-specific functional status measure for patients with coronary disease, and the Mental Health Inventory, a mental health screening instrument from the Short Form-36. Mental Health Inventory evidence of depression was associated with significantly worse disease-specific functional status. Depressed patients had more physical limitation (mean difference in Seattle Angina Questionnaire score = 16.9, P |
| doi_str_mv | 10.1067/mhj.2000.106600 |
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The study was designed as a cross-sectional survey and 3-month longitudinal cohort. Methods and Results The study took place in outpatient clinics of 3 Veterans Administration hospitals. All 7282 enrollees were surveyed and 4560 (62.6%) returned baseline questionnaires, including a screening instrument for depression. Thirty-nine percent (n = 1793) reported evidence of coronary artery disease and 1282 patients (71.5%) returned the Seattle Angina Questionnaire; 1025 patients (80%) completed a subsequent 3-month series of instruments. Main outcome measures used were the Seattle Angina Questionnaire, a valid, reliable, and responsive disease-specific functional status measure for patients with coronary disease, and the Mental Health Inventory, a mental health screening instrument from the Short Form-36. Mental Health Inventory evidence of depression was associated with significantly worse disease-specific functional status. Depressed patients had more physical limitation (mean difference in Seattle Angina Questionnaire score = 16.9, P <.001), more frequent angina (mean difference in Seattle Angina Questionnaire score = 9.5, P <.001), less satisfaction with their treatment for coronary artery disease (mean difference in Seattle Angina Questionnaire score = 9.9, P <.001), and lower perceived quality of life (mean difference in Seattle Angina Questionnaire score = 16.3, P <.001) than nondepressed patients. Frequency of depressive symptoms demonstrated an inverse relation with cardiac-specific functional status and when patients’ depression status changed over time, so did their cardiac-specific health status. Conclusions Depression is associated with significantly more physical limitation, more frequent angina, less treatment satisfaction, and lower perceived quality of life in outpatients with coronary artery disease. (Am Heart J 2000;140:105-10.)</description><identifier>ISSN: 0002-8703</identifier><identifier>EISSN: 1097-6744</identifier><identifier>DOI: 10.1067/mhj.2000.106600</identifier><identifier>PMID: 10874270</identifier><identifier>CODEN: AHJOA2</identifier><language>eng</language><publisher>New York, NY: Mosby, Inc</publisher><subject>Age Distribution ; Aged ; Angina Pectoris - epidemiology ; Angina Pectoris - psychology ; Biological and medical sciences ; Cardiology. Vascular system ; Cohort Studies ; Comorbidity ; Coronary Disease - diagnosis ; Coronary Disease - epidemiology ; Coronary Disease - psychology ; Coronary heart disease ; Cross-Sectional Studies ; Depressive Disorder - diagnosis ; Depressive Disorder - epidemiology ; Depressive Disorder - physiopathology ; Female ; Heart ; Humans ; Incidence ; Iowa - epidemiology ; Male ; Medical sciences ; Middle Aged ; Probability ; Quality of Life ; Reference Values ; Risk Assessment ; Severity of Illness Index ; Sex Distribution ; Sickness Impact Profile ; Surveys and Questionnaires</subject><ispartof>The American heart journal, 2000-07, Vol.140 (1), p.105-110</ispartof><rights>2000 Mosby, Inc.</rights><rights>2000 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-e3ff0cc2dbbe411a62c19c64f5f799ea8a6fc7443ff575e86279ce39af0b47723</citedby><cites>FETCH-LOGICAL-c372t-e3ff0cc2dbbe411a62c19c64f5f799ea8a6fc7443ff575e86279ce39af0b47723</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>309,310,314,780,784,789,790,23930,23931,25140,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1480490$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10874270$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Spertus, John A.</creatorcontrib><creatorcontrib>McDonell, Mary</creatorcontrib><creatorcontrib>Woodman, Catherine L.</creatorcontrib><creatorcontrib>Fihn, Stephan D.</creatorcontrib><title>Association between depression and worse disease-specific functional status in outpatients with coronary artery disease</title><title>The American heart journal</title><addtitle>Am Heart J</addtitle><description>Background The objective of this study was to determine if depression is associated with worse disease-specific functional status in patients with coronary artery disease. The study was designed as a cross-sectional survey and 3-month longitudinal cohort. Methods and Results The study took place in outpatient clinics of 3 Veterans Administration hospitals. All 7282 enrollees were surveyed and 4560 (62.6%) returned baseline questionnaires, including a screening instrument for depression. Thirty-nine percent (n = 1793) reported evidence of coronary artery disease and 1282 patients (71.5%) returned the Seattle Angina Questionnaire; 1025 patients (80%) completed a subsequent 3-month series of instruments. Main outcome measures used were the Seattle Angina Questionnaire, a valid, reliable, and responsive disease-specific functional status measure for patients with coronary disease, and the Mental Health Inventory, a mental health screening instrument from the Short Form-36. Mental Health Inventory evidence of depression was associated with significantly worse disease-specific functional status. Depressed patients had more physical limitation (mean difference in Seattle Angina Questionnaire score = 16.9, P <.001), more frequent angina (mean difference in Seattle Angina Questionnaire score = 9.5, P <.001), less satisfaction with their treatment for coronary artery disease (mean difference in Seattle Angina Questionnaire score = 9.9, P <.001), and lower perceived quality of life (mean difference in Seattle Angina Questionnaire score = 16.3, P <.001) than nondepressed patients. Frequency of depressive symptoms demonstrated an inverse relation with cardiac-specific functional status and when patients’ depression status changed over time, so did their cardiac-specific health status. Conclusions Depression is associated with significantly more physical limitation, more frequent angina, less treatment satisfaction, and lower perceived quality of life in outpatients with coronary artery disease. (Am Heart J 2000;140:105-10.)</description><subject>Age Distribution</subject><subject>Aged</subject><subject>Angina Pectoris - epidemiology</subject><subject>Angina Pectoris - psychology</subject><subject>Biological and medical sciences</subject><subject>Cardiology. Vascular system</subject><subject>Cohort Studies</subject><subject>Comorbidity</subject><subject>Coronary Disease - diagnosis</subject><subject>Coronary Disease - epidemiology</subject><subject>Coronary Disease - psychology</subject><subject>Coronary heart disease</subject><subject>Cross-Sectional Studies</subject><subject>Depressive Disorder - diagnosis</subject><subject>Depressive Disorder - epidemiology</subject><subject>Depressive Disorder - physiopathology</subject><subject>Female</subject><subject>Heart</subject><subject>Humans</subject><subject>Incidence</subject><subject>Iowa - epidemiology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Probability</subject><subject>Quality of Life</subject><subject>Reference Values</subject><subject>Risk Assessment</subject><subject>Severity of Illness Index</subject><subject>Sex Distribution</subject><subject>Sickness Impact Profile</subject><subject>Surveys and Questionnaires</subject><issn>0002-8703</issn><issn>1097-6744</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><recordid>eNp1kEFv1DAQRi0EotuWMzfkA-KW1naydnKsqtIiVeJCz5YzGauusnHwOKz49zhkJXrhNBr7zefxY-yjFFdSaHN9eH65UkL87bQQb9hOis5U2jTNW7YrF6pqjajP2DnRS2m1avV7diZFaxplxI4db4giBJdDnHiP-Yg48QHnhETrkZsGfoyJkA-B0BFWNCMEH4D7ZYJ1zI2csssL8TDxuOS5hOGUiR9DfuYQU0HSb-5SxlJOMZfsnXcj4YdTvWBPX-9-3D5Uj9_vv93ePFZQG5UrrL0XAGroe2ykdFqB7EA3fu9N16FrnfZQPluwvdljq5XpAOvOedE3xqj6gn3ZcucUfy5I2R4CAY6jmzAuZI1UtWg6WcDrDYQUiRJ6O6dwKItbKezq2hbXdnVtN9dl4tMpeukPOLziN7kF-HwCHIEbfXITBPrHNW15ecW6DcPi4VfAZAmKQMAhJIRshxj-u8Mfq6advg</recordid><startdate>20000701</startdate><enddate>20000701</enddate><creator>Spertus, John A.</creator><creator>McDonell, Mary</creator><creator>Woodman, Catherine L.</creator><creator>Fihn, Stephan D.</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20000701</creationdate><title>Association between depression and worse disease-specific functional status in outpatients with coronary artery disease</title><author>Spertus, John A. ; McDonell, Mary ; Woodman, Catherine L. ; Fihn, Stephan D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c372t-e3ff0cc2dbbe411a62c19c64f5f799ea8a6fc7443ff575e86279ce39af0b47723</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Age Distribution</topic><topic>Aged</topic><topic>Angina Pectoris - epidemiology</topic><topic>Angina Pectoris - psychology</topic><topic>Biological and medical sciences</topic><topic>Cardiology. Vascular system</topic><topic>Cohort Studies</topic><topic>Comorbidity</topic><topic>Coronary Disease - diagnosis</topic><topic>Coronary Disease - epidemiology</topic><topic>Coronary Disease - psychology</topic><topic>Coronary heart disease</topic><topic>Cross-Sectional Studies</topic><topic>Depressive Disorder - diagnosis</topic><topic>Depressive Disorder - epidemiology</topic><topic>Depressive Disorder - physiopathology</topic><topic>Female</topic><topic>Heart</topic><topic>Humans</topic><topic>Incidence</topic><topic>Iowa - epidemiology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Probability</topic><topic>Quality of Life</topic><topic>Reference Values</topic><topic>Risk Assessment</topic><topic>Severity of Illness Index</topic><topic>Sex Distribution</topic><topic>Sickness Impact Profile</topic><topic>Surveys and Questionnaires</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Spertus, John A.</creatorcontrib><creatorcontrib>McDonell, Mary</creatorcontrib><creatorcontrib>Woodman, Catherine L.</creatorcontrib><creatorcontrib>Fihn, Stephan D.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American heart journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Spertus, John A.</au><au>McDonell, Mary</au><au>Woodman, Catherine L.</au><au>Fihn, Stephan D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Association between depression and worse disease-specific functional status in outpatients with coronary artery disease</atitle><jtitle>The American heart journal</jtitle><addtitle>Am Heart J</addtitle><date>2000-07-01</date><risdate>2000</risdate><volume>140</volume><issue>1</issue><spage>105</spage><epage>110</epage><pages>105-110</pages><issn>0002-8703</issn><eissn>1097-6744</eissn><coden>AHJOA2</coden><abstract>Background The objective of this study was to determine if depression is associated with worse disease-specific functional status in patients with coronary artery disease. The study was designed as a cross-sectional survey and 3-month longitudinal cohort. Methods and Results The study took place in outpatient clinics of 3 Veterans Administration hospitals. All 7282 enrollees were surveyed and 4560 (62.6%) returned baseline questionnaires, including a screening instrument for depression. Thirty-nine percent (n = 1793) reported evidence of coronary artery disease and 1282 patients (71.5%) returned the Seattle Angina Questionnaire; 1025 patients (80%) completed a subsequent 3-month series of instruments. Main outcome measures used were the Seattle Angina Questionnaire, a valid, reliable, and responsive disease-specific functional status measure for patients with coronary disease, and the Mental Health Inventory, a mental health screening instrument from the Short Form-36. Mental Health Inventory evidence of depression was associated with significantly worse disease-specific functional status. Depressed patients had more physical limitation (mean difference in Seattle Angina Questionnaire score = 16.9, P <.001), more frequent angina (mean difference in Seattle Angina Questionnaire score = 9.5, P <.001), less satisfaction with their treatment for coronary artery disease (mean difference in Seattle Angina Questionnaire score = 9.9, P <.001), and lower perceived quality of life (mean difference in Seattle Angina Questionnaire score = 16.3, P <.001) than nondepressed patients. Frequency of depressive symptoms demonstrated an inverse relation with cardiac-specific functional status and when patients’ depression status changed over time, so did their cardiac-specific health status. Conclusions Depression is associated with significantly more physical limitation, more frequent angina, less treatment satisfaction, and lower perceived quality of life in outpatients with coronary artery disease. (Am Heart J 2000;140:105-10.)</abstract><cop>New York, NY</cop><pub>Mosby, Inc</pub><pmid>10874270</pmid><doi>10.1067/mhj.2000.106600</doi><tpages>6</tpages></addata></record> |
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| ispartof | The American heart journal, 2000-07, Vol.140 (1), p.105-110 |
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| subjects | Age Distribution Aged Angina Pectoris - epidemiology Angina Pectoris - psychology Biological and medical sciences Cardiology. Vascular system Cohort Studies Comorbidity Coronary Disease - diagnosis Coronary Disease - epidemiology Coronary Disease - psychology Coronary heart disease Cross-Sectional Studies Depressive Disorder - diagnosis Depressive Disorder - epidemiology Depressive Disorder - physiopathology Female Heart Humans Incidence Iowa - epidemiology Male Medical sciences Middle Aged Probability Quality of Life Reference Values Risk Assessment Severity of Illness Index Sex Distribution Sickness Impact Profile Surveys and Questionnaires |
| title | Association between depression and worse disease-specific functional status in outpatients with coronary artery disease |
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