A Comparison of Time to Positive Culture and Time to Clinical Identification of Serious Bacterial Infection in Infants

To compare the time to positive culture with the time to clinical detection of serious bacterial infection (SBI) in young infants, a retrospective case series of 949 infants age 0-60 days, who had a body fluid cultured in the emergency department or within 24 hours of admission was analyzed. Times t...

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Bibliographic Details
Published in:Clinical pediatrics 2003-11, Vol.42 (9), p.797-805
Main Authors: Brown, Julie C., Del Beccaro, Mark A., Clausen, Carla R.
Format: Article
Language:English
Subjects:
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Babies
Bacteria
Bacteria - isolation & purification
Bacterial infections
Bacterial Infections - diagnosis
Biological and medical sciences
Diagnosis
Emergency and intensive care: neonates and children. Prematurity. Sudden death
Emergency Medical Services
Female
Human viral diseases
Humans
Infant
Infant, Newborn
Infections
Infectious diseases
Intensive care medicine
Male
Medical sciences
Time
Time Factors
Viral diseases
Viral diseases of the respiratory system and ent viral diseases
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Summary:To compare the time to positive culture with the time to clinical detection of serious bacterial infection (SBI) in young infants, a retrospective case series of 949 infants age 0-60 days, who had a body fluid cultured in the emergency department or within 24 hours of admission was analyzed. Times to first report of positive culture and first clinical diagnosis of SBI were compared. Of 44 infants with positive cultures, 48% were clinically diagnosed with SBI at first evaluation. Of 21 infants with cultures reported positive after 24 hours, 14 were already diagnosed with SBI. Infections that altered therapy were identified after 24 and 36 hours in 4 infants and 1 infant, respectively. In infants with SBIs, the time to positive culture is longer than the time to identification of infection.
ISSN:0009-9228
1938-2707
DOI:10.1177/000992280304200905