Postoperative muscle paralysis after rocuronium: less residual block when acceleromyography is used

Background: Residual muscle paralysis after anesthesia is common after pancuronium, but less common following the intermediate‐acting drugs vecuronium and atracurium. Therefore, many anesthetists do not monitor neuromuscular function when using an intermediate‐acting agent. The purpose of this prosp...

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Bibliographic Details
Published in:Acta anaesthesiologica Scandinavica 2002-02, Vol.46 (2), p.207-213
Main Authors: Gätke, M. R., Viby-Mogensen, J., Rosenstock, C., Jensen, F. S., Skovgaard, L. T.
Format: Article
Language:English
Subjects:
acceleromyography
Adolescent
Adult
Aged
Androstanols - pharmacology
Anesthesia
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Double-Blind Method
Female
General anesthesia. Technics. Complications. Neuromuscular blocking. Premedication. Surgical preparation. Sedation
Humans
Male
mechanomyography
Medical sciences
Middle Aged
monitoring
Monitoring, Physiologic - methods
Myography - methods
neuromuscular block
neuromuscular function
Neuromuscular Junction - drug effects
Neuromuscular Junction - physiology
Neuromuscular Nondepolarizing Agents - pharmacology
objective neuromuscular transmission monitoring device
Prospective Studies
residual curarization
Rocuronium
Time Factors
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Summary:Background: Residual muscle paralysis after anesthesia is common after pancuronium, but less common following the intermediate‐acting drugs vecuronium and atracurium. Therefore, many anesthetists do not monitor neuromuscular function when using an intermediate‐acting agent. The purpose of this prospective, randomised and double‐blind study was to establish the incidence and degree of postoperative residual block following the use of rocuronium in patients not monitored with a nerve stimulator, and to compare it with results obtained in patients monitored using acceleromyography (AMG). Methods: During propofol/opioid anesthesia, 120 adult patients were randomised to two groups, one monitored with AMG, the other using only clinical criteria without a nerve stimulator. Postoperatively, TOF‐ratio was measured with mechanomyography; a TOF‐ratio
ISSN:0001-5172
1399-6576
DOI:10.1034/j.1399-6576.2002.460216.x