Soluble fiber intake at a dose approved by the US Food and Drug Administration for a claim of health benefits: serum lipid risk factors for cardiovascular disease assessed in a randomized controlled crossover trial

Background: The US Food and Drug Administration (FDA) approved health claims for 2 dietary fibers, β-glucan (0.75 g/serving) and psyllium (1.78 g/serving), on the assumption that 4 servings/d would reduce cardiovascular disease risk. Objective: We assessed the efficacy of this dose of fibers in redu...

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Bibliographic Details
Published in:The American journal of clinical nutrition 2002-05, Vol.75 (5), p.834-839
Main Authors: Jenkins, David J.A, Kendall, Cyril W.C, Vuksan, Vladimir, Vidgen, Edward, Parker, Tina, Faulkner, Dorothea, Mehling, Christine C, Garsetti, Marcella, Testolin, Giulio, Cunnane, Stephen C, Ryan, Mary Ann, Corey, Paul N
Format: Article
Language:English
Subjects:
Adult
adults
Aged
Aged, 80 and over
Apolipoproteins - blood
beta-glucans
Biological and medical sciences
blood
blood lipids
blood pressure
Blood Pressure - drug effects
Cardiovascular disease
Cardiovascular Diseases - etiology
Cholesterol
Clinical trials
Cross-Over Studies
Dietary fiber
Dietary Fiber - administration & dosage
Dietary Fiber - pharmacology
Disorders of blood lipids. Hyperlipoproteinemia
Dose-Response Relationship, Drug
Drug Approval
energy
fasting
Female
Food and Drug Administration
foods
gastrointestinal system
Glucans - administration & dosage
Glucans - pharmacology
health claims
Health Status
high fiber diet
Humans
Lipids - blood
Male
Medical sciences
Metabolic diseases
Middle Aged
palatability
Prevention
Psyllium - administration & dosage
Psyllium - pharmacology
risk
Risk Assessment
Risk Factors
risk reduction
Solubility
soluble fiber
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Summary:Background: The US Food and Drug Administration (FDA) approved health claims for 2 dietary fibers, β-glucan (0.75 g/serving) and psyllium (1.78 g/serving), on the assumption that 4 servings/d would reduce cardiovascular disease risk. Objective: We assessed the efficacy of this dose of fibers in reducing serum lipid risk factors for cardiovascular disease. Design: Sixty-eight hyperlipidemic adults consumed a test (high-fiber) and a control low-fat (25% of energy), low-cholesterol (
ISSN:0002-9165
1938-3207
DOI:10.1093/ajcn/75.5.834