Cognitive and behavioural functioning in men with schizophrenia both before and shortly after first admission to hospital: Cross-sectional analysis

The extent of premorbid changes associated with the onset of schizophrenia are debated. The study examined cognitive and behavioural functioning prior to, and after, first hospitalisation for schizophrenia. Data from the Israeli Draft Board Register of intelligence, social functioning and behaviour...

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Bibliographic Details
Published in:British journal of psychiatry 2000-07, Vol.177 (1), p.26-32
Main Authors: RABINOWITZ, JONATHAN, REICHENBERG, AVI, WEISER, MARK, MARK, MORDECHAI, KAPLAN, ZEEV, DAVIDSON, MICHAEL
Format: Article
Language:English
Subjects:
Adolescent
Case-Control Studies
Cognition & reasoning
Cognition Disorders - physiopathology
Cognitive ability
Cognitive-behavioral factors
Disease Progression
Hospitalization
Humans
Intelligence
Intelligence tests
Israel
Male
Matrices
Men
Mental disorders
Mental Disorders - physiopathology
Population
Premorbid
Psychiatry
Psychosis
Schizophrenia
Schizophrenic Psychology
Social behavior
Social functioning
Time Factors
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Summary:The extent of premorbid changes associated with the onset of schizophrenia are debated. The study examined cognitive and behavioural functioning prior to, and after, first hospitalisation for schizophrenia. Data from the Israeli Draft Board Register of intelligence, social functioning and behaviour testing for all Israeli males aged 16-17 was linked with data from the National Psychiatric Hospitalisation Case Register. This identified 692 men who had been admitted to hospital for schizophrenia. Cases and non-cases matched on age and school were compared, as were cases aggregated by the time that had elapsed between testing and first admission to hospital. Cases performed worse than non-cases on all measures. On Social Functioning and on Raven's Progressive Matrices-R, differences between cases and non-cases were progressively greater for cases admitted closer to the time of testing. These differences were greatest for persons tested after first psychiatric hospitalisation. The results confirm premorbid deficits associated with schizophrenia and support the hypothesis that decline is progressive.
ISSN:0007-1250
1472-1465
DOI:10.1192/bjp.177.1.26