Case of optic nerve involvement in metastasis of a gastrointestinal stromal tumor

The gastrointestinal stromal tumor (GIST) belongs to the leiomyosarcoma or leiomyoma group, and metastasis of leiomyosarcoma to the orbit is extremely rare. The most common sign of the metastasis of leiomyosarcoma to the orbit is proptosis; the primary lesion is usually found in skin or soft tissue....

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Bibliographic Details
Published in:Japanese journal of ophthalmology 2004-03, Vol.48 (2), p.166-168
Main Authors: Akiyama, Kazuhide, Numaga, Jiro, Kagaya, Fumie, Takazawa, Yutaka, Suzuki, Shigenobu, Koseki, Nobuyuki, Kato, Satoshi, Kaburaki, Toshikatsu, Kawashima, Hidetoshi
Format: Article
Language:English
Subjects:
Fatal Outcome
Humans
Intestinal Neoplasms - pathology
Intestine, Small - pathology
Leiomyosarcoma - diagnostic imaging
Leiomyosarcoma - secondary
Liver Neoplasms - secondary
Lumbosacral Region - pathology
Male
Middle Aged
Optic Nerve Neoplasms - diagnostic imaging
Optic Nerve Neoplasms - secondary
Spinal Neoplasms - secondary
Tomography, X-Ray Computed
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Summary:The gastrointestinal stromal tumor (GIST) belongs to the leiomyosarcoma or leiomyoma group, and metastasis of leiomyosarcoma to the orbit is extremely rare. The most common sign of the metastasis of leiomyosarcoma to the orbit is proptosis; the primary lesion is usually found in skin or soft tissue. A 60-year-old man, who had a history of multiple metastases of GIST, suffered sudden unilateral blindness. His history and computed tomographic scans suggested that the lesion was a metastasis of GIST to the cavernous sinus around the root of the optic nerve. To the best of our knowledge, this is the first case of metastasis of GIST to the orbit.
ISSN:0021-5155
1613-2246
DOI:10.1007/s10384-003-0028-9