The extent of resection influences outcome following hepatectomy for colorectal liver metastases

Background. The acceptable indications for liver resection in patients with colorectal metastases have increased significantly in the last decade. It is thus becoming more difficult to ascertain the limitations for selection as the boundaries have been greatly extended. This has resulted in not only...

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Bibliographic Details
Published in:European journal of surgical oncology 2004-05, Vol.30 (4), p.370-376
Main Authors: Stewart, G.D., O'Súilleabháin, C.B., Madhavan, K.K., Wigmore, S.J., Parks, R.W., Garden, O.J.
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Colorectal Neoplasms - mortality
Colorectal Neoplasms - pathology
Colorectal Neoplasms - surgery
Female
Hepatectomy
Hepatectomy - methods
Humans
Kruskal–Wallis test
Liver Neoplasms - mortality
Liver Neoplasms - secondary
Liver Neoplasms - surgery
Liver resection
Male
Metastases
Middle Aged
Neoplasm Recurrence, Local
Post-operative stay
Postoperative Complications
Pulmonary Embolism - etiology
Survival
Survival Analysis
Treatment Outcome
Trisectionectomy
Wedge resection
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Summary:Background. The acceptable indications for liver resection in patients with colorectal metastases have increased significantly in the last decade. It is thus becoming more difficult to ascertain the limitations for selection as the boundaries have been greatly extended. This has resulted in not only more extensive resections, but more atypical and bilobar resections. The aim of this study was to compare the outcome of patients undergoing different extent of liver resection in a specialist unit. Methods. All patients undergoing liver resection for colorectal metastases at the Royal Infirmary of Edinburgh between October 1988 and April 2001 were reviewed. Patients were allocated into one of three groups: standard group, extended group, and segmental group. Patient information was collected from a prospectively completed database. Results. One hundred and thirty-seven patients had liver resections for colorectal metastases during the study period. There were 69 standard hepatectomies, 41 extended resections and 27 segmental resections. CEA level was significantly lower in the segmental group ( p=0.012). There was a significant difference between the groups in terms of median operating time ( p
ISSN:0748-7983
1532-2157
DOI:10.1016/j.ejso.2004.01.011