A case of Pasteurella multocida peritoneal dialysis-associated peritonitis and review of the literature

• Published in: International journal of infectious diseases 2004-05, Vol.8 (3), p.171-174
• Main Authors: Cooke, Fiona J, Kodjo, Angeli, Clutterbuck, Elaine J, Bamford, Kathleen B
• Format: Article
• Language: English
• Subjects: Aged; Animals; Biological and medical sciences; Cat; Cats; Female; Fundamental and applied biological sciences. Psychology; Humans; Infection; Infectious diseases; Kidney Failure, Chronic - therapy; Medical sciences; Microbiology; Pasteurella Infections - microbiology; Pasteurella multocida; Pasteurella multocida - classification; Pasteurella multocida - genetics; Pasteurella multocida - isolation & purification; Peritoneal dialysis; Peritoneal Dialysis, Continuous Ambulatory - instrumentation; Peritonitis; Peritonitis - microbiology; Renal failure
• ISSN: 1201-9712; 1878-3511
• DOI: 10.1016/j.ijid.2003.10.004

Objectives: Two episodes of peritoneal dialysis-associated peritonitis, which occurred four months apart and were both due to Pasteurella multocida, were noted in a 73 year old woman. This report aims to describe the clinical history of these episodes and the microbiological investigations that were undertaken. The relevant literature will also be discussed. Methods and results: Basic microbiological tests identified the organism as Pasteurella multocida, and further work at a specialist laboratory classified it as Pasteurella multocida subsp. multocida. Pulsed field gel electrophoresis confirmed that the strains isolated from the two clinical episodes originated from the same clone. A literature search was performed, looking particularly for patients who experienced more than one episode of peritonitis caused by Pasteurella spp, whether due to recurrence or re-infection. Conclusions: It is likely that the infection resulted from a domestic cat, as there was evidence of a cat bite to the dialysis tubing in the period between the two episodes. Re-infection with two identical strains of pasteurella is more probable than relapse, for reasons discussed. Strict hygiene and avoiding contact between dialysis tubing and domestic animals must be emphasised to try to prevent pasteurella and other animal-associated infections in this already vulnerable population.