Previous chemotherapy as a predictor of wound infections in nonmajor head and neck surgery: Results of a prospective study

Background. The goal of this prospective study was to determine the incidence of wound infections (WI) after clean uncontaminated head and neck cancer procedures and after emergency tracheotomies. Methods. Two hundred twelve clean procedures without tracheotomy or opening of mucosa (neck dissections...

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Bibliographic Details
Published in:Head & neck 2004-06, Vol.26 (6), p.513-517
Main Authors: Penel, Nicolas, Fournier, Charles, Lefebvre, Danièle, Roussel-Delvallez, Micheline, Sarini, Jérome, Kara, Ahmed, Mallet, Yann, Lefebvre, Jean-Louis
Format: Article
Language:English
Subjects:
Aged
Antineoplastic Agents - adverse effects
Biological and medical sciences
chemotherapy
Female
head and neck cancer
Head and Neck Neoplasms - drug therapy
Humans
Incidence
Klebsiella oxytoca - isolation & purification
Male
Medical sciences
Neck - surgery
Neck Dissection - adverse effects
nosocomial infection
Otorhinolaryngology (head neck, general aspects and miscellaneous)
Otorhinolaryngology. Stomatology
Parotid Gland - surgery
Prospective Studies
Risk Factors
Staphylococcus aureus - isolation & purification
Streptococcus agalactiae - isolation & purification
Surgical Wound Infection - epidemiology
Surgical Wound Infection - etiology
Thyroidectomy - adverse effects
tracheotomy
Tumors
wound infection
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Summary:Background. The goal of this prospective study was to determine the incidence of wound infections (WI) after clean uncontaminated head and neck cancer procedures and after emergency tracheotomies. Methods. Two hundred twelve clean procedures without tracheotomy or opening of mucosa (neck dissections, large skin resections, thyroidectomies, parotid gland resections, and explorative cervicotomies) were studied at Oscar Lambret Cancer Center over a 24‐month period. Results. WI rate was 6.6% (14 of 212). In a univariate analysis, only one variable was significantly related to the likelihood of WI: previous anticancer chemotherapy. All but one patient who had had previous chemotherapy demonstrated WI (14 of 15). Conclusions. After previous chemotherapy, WI rate in clean uncontaminated head and neck surgery was as high as 90%. In this case, antibiotic prophylaxis should be evaluated. © 2004 Wiley Periodicals, Inc. Head Neck 26: 513–517, 2004
ISSN:1043-3074
1097-0347
DOI:10.1002/hed.20002