Early Extubation and Nasal Continuous Positive Airway Pressure After Surfactant Treatment for Respiratory Distress Syndrome Among Preterm Infants <30 Weeks' Gestation

To test the hypothesis that preterm infants with infant respiratory distress syndrome who are treated with nasal continuous positive airway pressure (NCPAP) and surfactant administration followed by immediate extubation and NCPAP application (SURF-NCPAP group) demonstrate less need for mechanical ve...

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Bibliographic Details
Published in:Pediatrics (Evanston) 2004-06, Vol.113 (6), p.e560-e563
Main Authors: Dani, Carlo, Bertini, Giovanna, Pezzati, Marco, Cecchi, Alessandra, Caviglioli, Cosimo, Rubaltelli, Firmino F
Format: Article
Language:English
Subjects:
Continuous Positive Airway Pressure
Female
Humans
Infant, Newborn
Infant, Premature
Infant, Very Low Birth Weight
Length of Stay
Male
Oxygen Inhalation Therapy
Prospective Studies
Pulmonary Surfactants - therapeutic use
Respiration, Artificial
Respiratory Distress Syndrome, Newborn - complications
Respiratory Distress Syndrome, Newborn - mortality
Respiratory Distress Syndrome, Newborn - therapy
Ventilator Weaning
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Summary:To test the hypothesis that preterm infants with infant respiratory distress syndrome who are treated with nasal continuous positive airway pressure (NCPAP) and surfactant administration followed by immediate extubation and NCPAP application (SURF-NCPAP group) demonstrate less need for mechanical ventilation (MV), compared with infants who receive MV after surfactant administration (SURF-MV group). A prospective randomized study was conducted, in which infants
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.113.6.e560