Head-to-Head comparison between Contrast-Enhanced magnetic resonance imaging and dobutamine magnetic resonance imaging in men with ischemic cardiomyopathy

Contrast-enhanced magnetic resonance imaging (MRI) can predict functional recovery after revascularization. Segments with small, subendocardial scars have a large likelihood of recovery, and segments with transmural infarction have a small likelihood of recovery. Segments with an intermediate extent...

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Bibliographic Details
Published in:The American journal of cardiology 2004-06, Vol.93 (12), p.1461-1464
Main Authors: Kaandorp, Theodorus A.M, Bax, Jeroen J, Schuijf, Joanne D, Viergever, Eric P, van Der Wall, Ernst E, de Roos, Albert, Lamb, Hildo J
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biological and medical sciences
Cardiology. Vascular system
Cardiotonic Agents
Cardiovascular disease
Cicatrix - etiology
Cicatrix - pathology
Comparative analysis
Contrast Media
Coronary Artery Disease - pathology
Dobutamine
Heart
Humans
Hypokinesia - pathology
Magnetic Resonance Imaging - methods
Male
Medical sciences
Middle Aged
Myocardial Contraction - physiology
Myocardial Infarction - complications
Myocardial Infarction - pathology
Myocarditis. Cardiomyopathies
NMR
Nuclear magnetic resonance
Scars
Ventricular Dysfunction, Left - pathology
Ventricular Dysfunction, Left - physiopathology
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Summary:Contrast-enhanced magnetic resonance imaging (MRI) can predict functional recovery after revascularization. Segments with small, subendocardial scars have a large likelihood of recovery, and segments with transmural infarction have a small likelihood of recovery. Segments with an intermediate extent of infarction have an intermediate likelihood of recovery, and therefore, additional information is needed. Accordingly, the transmurality of infarction on contrast-enhanced MRI was compared with low-dose dobutamine MRI to further define viability in 48 patients. Regional contractile dysfunction was determined by cine MRI at rest (17-segment model), and contractile reserve was determined using low-dose dobutamine infusion. Contrast-enhanced MRI was performed to assess the extent of scar tissue. A total of 338 segments (41%) were dysfunctional, with 61% having contractile reserve. Most segments (approximately 75%) with small, subendocardial scars (hyperenhancement scores 1 or 2) had contractile reserve, whereas contractile reserve was not frequently (17%) observed in segments with transmural infarction (hyperenhancement score 4) (p
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2004.03.003