Reduction in Renal Function After Renal Arteriography and After Renal Artery Angioplasty

• Published in: European journal of vascular and endovascular surgery 2002-08, Vol.24 (2), p.156-160
• Main Authors: Sabeti, S., Schillinger, M., Mlekusch, W., Ahmadi and, R., Minar, E.
• Format: Article
• Language: English
• Subjects: Aged; Angiography - adverse effects; Angioplasty - adverse effects; Blood Vessel Prosthesis Implantation - adverse effects; Female; Humans; Incidence; Kidney - diagnostic imaging; Kidney - physiopathology; Kidney - surgery; Kidney Diseases - epidemiology; Kidney Diseases - etiology; Kidney Diseases - physiopathology; Male; Middle Aged; Postoperative Complications; Renal Artery - diagnostic imaging; Renal Artery - surgery; Renal Artery Obstruction - diagnostic imaging; Renal Artery Obstruction - physiopathology; Renal Artery Obstruction - surgery; Renal, Artery, Angiography, Angioplasty, Renal deterioration, Risk factors; Retrospective Studies; Risk Factors; Stents - adverse effects
• ISSN: 1078-5884; 1532-2165
• DOI: 10.1053/ejvs.2002.1655

Objective: to investigate the incidence and risk factors for renal function deterioration after renal angiography and angioplasty or stenting. Methods: a retrospective study of 85 consecutive patients undergoing selective renal artery arteriography (n=53) or renal artery angioplasty % (PTRA) stenting (n=32) for renal artery stenosis. Multivariate logistic regression analysis was used to determine independent predictors of deterioration of renal function, defined as an increase of serum creatinine by at least one third within 24h. Results: deterioration of renal function occurred in 13 patients (15%), [8/53 (15%) after angiography and 5/32 (16%) after PTRA/stenting]. Only pre-existing renal impairment (se-creatinine≥177μmol/l) (Odds ratio: 40; 95% confidence interval 1.2–72, p=0.02) and administered dosage of contrast agent (more than 225ml) (OR 67; 95% CI1 1.8–100, p=0.02) were independently associated with renal function deterioration. Conclusion: transient renal dysfunction after renal artery angiography or PTRA/stenting occurs in about 15% of patients, but persistent renal failure is uncommon. Pre-existing renal impairment and amount of contrast agent are independent risk factors. Endovascular treatment of renal artery stenosis is not associated with a higher risk of renal deterioration compared to selective renal angiography.