Human area V5 and motion in the ipsilateral visual field

We have studied area V5 of the human brain with visually‐evoked potential (VEP) and functional magnetic resonance imaging (fMRI) methods, using hemifield motion stimuli. Our results confirmed the presence of an ipsilateral field representation in V5 and found: (i) a delay in the ipsilateral response...

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Bibliographic Details
Published in:The European journal of neuroscience 2000-08, Vol.12 (8), p.3015-3025
Main Authors: Ffytche, D. H., Howseman, A., Edwards, R., Sandeman, D. R., Zeki, S.
Format: Article
Language:English
Subjects:
Adult
Brain Mapping
corpus callosum
Corpus Callosum - physiology
dynamic parallelism
Evoked Potentials, Visual - physiology
fMRI
Functional Laterality - physiology
Hemianopsia - physiopathology
Humans
Magnetic Resonance Imaging
Male
motion
Motion Perception - physiology
Space life sciences
VEP
visual cortex
Visual Cortex - physiology
Visual Fields - physiology
Visual Pathways - physiology
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Summary:We have studied area V5 of the human brain with visually‐evoked potential (VEP) and functional magnetic resonance imaging (fMRI) methods, using hemifield motion stimuli. Our results confirmed the presence of an ipsilateral field representation in V5 and found: (i) a delay in the ipsilateral response in V5, irrespective of the hemifield stimulated; (ii) a longer ipsilateral delay for left hemifield than for right hemifield stimulation; and (iii) in a patient with a section of the splenium, an absent ipsilateral response for right but not left hemifield stimulation. Together with neurophysiological and anatomical evidence in the monkey, our non‐invasive spatial and temporal imaging studies in man reveal that ipsilateral V5 is activated by motion signals transferred from contralateral V5. The asymmetry of ipsilateral delay in normal subjects and the asymmetrical loss of ipsilateral response following splenial section imply that signals related to visual motion are transferred from one V5 to the other through two segregated pathways.
ISSN:0953-816X
1460-9568
DOI:10.1046/j.1460-9568.2000.00177.x