The Role of Preoperative Tc-99m HMPAO-Labeled Leukocyte Total-Body Scans in Aortic Prosthetic Reconstruction

PURPOSE This study was performed to evaluate the utility of Tc-99m HMPAO-labeled leukocyte total-body scans (TBLS) for detecting remote septic foci before operation in patients undergoing aortofemoral vascular surgery. MATERIALS AND METHODS Fifty-eight patients were screened before operation for inf...

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Bibliographic Details
Published in:Clinical nuclear medicine 2001-12, Vol.26 (12), p.1024-1027
Main Authors: Liberatore, Mauro, Fiore, Vittorio, Iurilli, Anna Paola, Santini, Claudio, Baiocchi, Pia, Galiè, Maurizia, Schioppa, Annalisa, Rizzo, Luigi, Fiorani, Paolo
Format: Article
Language:English
Subjects:
Aged
Aortic Aneurysm, Abdominal - diagnostic imaging
Aortic Aneurysm, Abdominal - surgery
Aortic Aneurysm, Thoracic - diagnostic imaging
Aortic Aneurysm, Thoracic - surgery
Biological and medical sciences
Blood Vessel Prosthesis Implantation
Cardiovascular system
Female
Humans
Investigative techniques, diagnostic techniques (general aspects)
Leukocytes
Male
Medical sciences
Preoperative Care
Radionuclide Imaging
Radionuclide investigations
Radiopharmaceuticals
Technetium Tc 99m Exametazime
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Summary:PURPOSE This study was performed to evaluate the utility of Tc-99m HMPAO-labeled leukocyte total-body scans (TBLS) for detecting remote septic foci before operation in patients undergoing aortofemoral vascular surgery. MATERIALS AND METHODS Fifty-eight patients were screened before operation for inflammatory or infective disease, and a clinical score was assigned to each patient. Each patient had TBLSs. The relation between the clinical score and the TBLS result was determined. Patients with positive results of the TBLSs were examined, and the causes of these findings were treated before surgery. RESULTS Ten of the 58 (17%) patients had a positive result of TBLSs. Of 31 patients with a clinical score of zero, 3 had positive findings of TBLS. No TBLS was positive in the 13 patients with a clinical score of 1. TBLS findings were positive in 7 of 14 of the combined patients with clinical scores of 2, 3, or 4. None of the patients showed signs of prosthetic vascular graft infection during the postoperative follow-up period. CONCLUSIONS In conclusion, TBLSs can be used before aortofemoral vascular surgery, but only in patients with high clinical scores for inflammatory or infective disease to identify relevant infective foci that could cause vascular graft infection.
ISSN:0363-9762
1536-0229
DOI:10.1097/00003072-200112000-00007