Bacterial penetration into tonsillar surface epithelium during infectious mononucleosis

Bacterial penetration into epithelial cells, scraped from the palatine tonsils of 14 patients (10 males, four females; median age 16 years) with current infectious mononucleosis and concomitant membranous tonsillitis, was studied using the transmission electron microscopic (TEM) technique. Bacteria...

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Bibliographic Details
Published in:Journal of laryngology and otology 2000-11, Vol.114 (11), p.848-852
Main Authors: Räisänen, Simo, Myklebust, Reidar, Bye, Helga-Marie, Stenfors, Lars-Eric
Format: Article
Language:English
Subjects:
(RF) Otorhinolaryngology
Abscess
Abscesses
Adolescent
Adult
Airway management
Bacteria
Bacterial diseases
Biological and medical sciences
Ent and stomatologic bacterial diseases
Ent. Stomatology
Epithelial Cells - microbiology
Epithelial Cells - ultrastructure
Epstein-Barr
Epstein-Barr virus
Female
Human bacterial diseases
Humans
Infections
Infectious diseases
Infectious Mononucleosis - complications
Investigative techniques, diagnostic techniques (general aspects)
Lymphoma
Male
Medical sciences
Microscopy, Electron
Mononucleosis
Morphology
Opportunistic Infections - complications
Opportunistic Infections - microbiology
Palatine Tonsil - microbiology
Palatine Tonsil - ultrastructure
Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques
Patients
Peritonsillar
Physiology
Streptococcal
Streptococcal Infections - complications
Streptococcus - isolation & purification
Tonsil
Tonsillitis
Tonsillitis - microbiology
Virus
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Summary:Bacterial penetration into epithelial cells, scraped from the palatine tonsils of 14 patients (10 males, four females; median age 16 years) with current infectious mononucleosis and concomitant membranous tonsillitis, was studied using the transmission electron microscopic (TEM) technique. Bacteria were seen to adhere to and penetrate the epithelial cells, some of which were completely filled with bacteria. This finding suggests intracellular proliferation of bacteria. Epstein – Barr virus, the causative agent of infectious mononucleosis, especially when associated with growth of β-haemolytic streptococci on the palatine tonsils, induces bacterial penetration into tonsillar tissue, that in turn might be a causative mechanism in the development of peritonsillar abscess.
ISSN:0022-2151
1748-5460
DOI:10.1258/0022215001904149