RIB CAGE CONTRIBUTION TO RESTING AND CARBON DIOXIDE STIMULATED VENTILATION DURING 1 MAC ISOFLURANE ANAESTHESIA

Using respiratory inductive plethysmography, we have measured rib cage and abdominal motion during isoflurane anaesthesia in 16 healthy day-surgery patients. Anaesthesia was induced with propofol and maintained with 1 MAC isoflurane in air-oxygen via a laryngeal mask. Measurements were taken during...

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Bibliographic Details
Published in:British journal of anaesthesia : BJA 1991-12, Vol.67 (6), p.712-721
Main Authors: LUMB, A.B., PETROS, A.J., NUNN, J.F.
Format: Article
Language:English
Subjects:
Abdominal Muscles - physiology
Adolescent
Adult
Anaesthetics
Anesthesia, Inhalation
Anesthetics. Neuromuscular blocking agents
Biological and medical sciences
Body Mass Index
Carbon Dioxide - physiology
Humans
Isoflurane - pharmacology
Measurement techniques: respiratory inductive plethysmography
Medical sciences
Movement - drug effects
Neuropharmacology
Pharmacology. Drug treatments
Respiration - physiology
Respiratory Mechanics - drug effects
Ribs - physiology
Tidal Volume - physiology
Ventilation: rib cage motion
Vital Capacity
volatile: isoflurane
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Summary:Using respiratory inductive plethysmography, we have measured rib cage and abdominal motion during isoflurane anaesthesia in 16 healthy day-surgery patients. Anaesthesia was induced with propofol and maintained with 1 MAC isoflurane in air-oxygen via a laryngeal mask. Measurements were taken during both resting ventilation and hyperpnoea induced by rebreathing carbon dioxide. For resting ventilation, the rib cage contributed a mean (sd) of 33 (15) % of the total ventilation whilst awake, and 39 (12) % during anaesthesia (ns). With increasing end-tidal carbon dioxide whilst awake, the subjects showed a mean increase in the percentage rib cage contribution of 7.1 (12.5)%lkPa of carbon dioxide. With isoflurane anaesthesia, there was significant depression of this rib cage recruitment with the mean contribution decreasing by 3.6 (7.4) % kPa−1(P < 0.05). These results indicate that 1 MAC of isoflurane does not selectively depress rib cage motion, except during carbon dioxide stimulated hyperpnoea.
ISSN:0007-0912
1471-6771
DOI:10.1093/bja/67.6.712