Biological Models and Genes of Tumor Reversion: Cellular Reprogramming through tpt1/TCTP and SIAH-1

Tumor reversion is the process by which some cancer cells lose their malignant phenotype. This study was aimed at defining some of the molecular and phenotypic properties of this process. Biological models of tumor reversion were isolated from human leukemia and breast cancer cell lines by using the...

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Bibliographic Details
Published in:Proceedings of the National Academy of Sciences - PNAS 2002-11, Vol.99 (23), p.14976-14981
Main Authors: Tuynder, Marcel, Susini, Laurent, Prieur, Sylvie, Besse, Stéphanie, Fiucci, Giusy, Amson, Robert, Telerman, Adam
Format: Article
Language:English
Subjects:
Basement Membrane - pathology
Biochemistry, Molecular Biology
Biological Sciences
Biology
Biomarkers, Tumor - genetics
Bionics
Breast Neoplasms
Cancer
Cell lines
Cellular Biology
Complementary DNA
Daughter cells
DNA, Antisense - genetics
DNA, Neoplasm - genetics
Female
Gene Expression Regulation, Neoplastic
Genes
Genetics
Human health and pathology
Humans
K562 Cells
Leukemia
Life Sciences
Models, Genetic
Neoplasms - genetics
Nuclear Proteins - genetics
Parvovirus
Phenotypes
Recombinant Proteins - metabolism
RNA, Small Interfering - genetics
Small interfering RNA
Transfection
Tumor cell line
Tumor Cells, Cultured
Tumors
U937 Cells
Ubiquitin-Protein Ligases
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