RNA editing of sorghum mitochondrial atp6 transcripts changes 15 amino acids and generates a carboxy-terminus identical to yeast

Sequencing of sorghum mitochondrial atp6 cDNA clones revealed 19 C-to-U transcript editing events within a 756 bp-conserved core gene; three were silent and 16 resulted in 15 amino acid changes. Only one edit, which was silent, was found in the 381 bp amino-extension to the core gene. Eleven of the...

Full description

Saved in:
Bibliographic Details
Published in:Current genetics 1991-11, Vol.20 (5), p.417-422
Main Authors: Kempken, F. (Florida Univ., Gainesville (USA). Dept. of Plant Pathology and United States Dept. of Agriculture/Agricultural Research Service), Mullen, J.A, Pring, D.R, Tang, H.V
Format: Article
Language:English
Subjects:
ACIDE AMINE
ADENOSINE TRIPHOSPHATE
ADENOSINTRIFOSFATO
AMINO ACIDS
AMINOACIDOS
ARN
atp6
Base Sequence
Biological and medical sciences
Cloning, Molecular
DNA, Mitochondrial
Edible Grain
Fundamental and applied biological sciences. Psychology
Genetic Variation
MITOCHONDRIA
Mitochondria - metabolism
MITOCHONDRIE
MITOCONDRIA
Molecular and cellular biology
Molecular genetics
Molecular Sequence Data
Proton-Translocating ATPases - genetics
Proton-Translocating ATPases - metabolism
RNA
RNA Processing, Post-Transcriptional
Saccharomyces cerevisiae - genetics
Sequence Homology, Nucleic Acid
SORGHUM BICOLOR
Sorghum mitochondria
Transcript editing
Transcription, Genetic
Transcription. Transcription factor. Splicing. Rna processing
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Sequencing of sorghum mitochondrial atp6 cDNA clones revealed 19 C-to-U transcript editing events within a 756 bp-conserved core gene; three were silent and 16 resulted in 15 amino acid changes. Only one edit, which was silent, was found in the 381 bp amino-extension to the core gene. Eleven of the 15 changed amino acids were identical with or else represented conservative changes compared to yeast atp6. Editing of a CAA codon to TAA truncates the carboxy-terminus to a position identical to that of yeast. The frequency of editing at sites which change amino acids was very high in contrast to partial editing at silent, third base, sites.
ISSN:0172-8083
1432-0983
DOI:10.1007/bf00317071