Prognosis of parathyroid function after minimally invasive radioguided parathyroidectomy (MIRP) and percutaneous ethanol injection therapy (PEIT) for primary hyperparathyroidism

During parathyroidectomy (PTx) for primary hyperparathyroidism (PHP), we surgically explored the contralateral parathyroid glands as well as those whose localization was clarified by ultrasonography and parathyroid scintigraphy. Although it is important to explore the contralateral side and other gl...

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Bibliographic Details
Published in:Biomedicine & pharmacotherapy 2002, Vol.56, p.41s-47s
Main Authors: KAKUTA, Takatoshi, SUZUKI, Yutaka, TADAKI, Futoshi, UEMURA, Katsuya, TANAKA, Reika, TANAKA, Shinichi, KUBOTA, Mitsuhiro, SAKAI, Hideto, KUROKAWA, Kiyoshi, SAITO, Akira
Format: Article
Language:English
Subjects:
Administration, Cutaneous
Adult
Aged
Biological and medical sciences
Ethanol - administration & dosage
Female
Follow-Up Studies
Humans
Hyperparathyroidism - diagnostic imaging
Hyperparathyroidism - drug therapy
Hyperparathyroidism - surgery
Male
Medical sciences
Middle Aged
Parathyroidectomy - instrumentation
Parathyroidectomy - methods
Prognosis
Radionuclide Imaging
Statistics, Nonparametric
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of endocrine glands
Technetium Tc 99m Sestamibi
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Summary:During parathyroidectomy (PTx) for primary hyperparathyroidism (PHP), we surgically explored the contralateral parathyroid glands as well as those whose localization was clarified by ultrasonography and parathyroid scintigraphy. Although it is important to explore the contralateral side and other glands, we frequently treat only the gland whose localization is confirmed. Recently, we have performed minimally invasive radioguided parathyroidectomy (MIRP) that resects only one gland observed on the imaging under technetium 99m-labeled sestamibi (MIBI) scanning guidance after obtaining prior informed consent. In this surgery, even if recurrence is observed contralaterally, it is possible to apply a similar procedure to the contralateral side again. We examined six PHP patients who underwent MIRP and two PHP patients treated with percutaneous ethanol injection therapy (PEIT). The follow-up period was 2 years. PEIT was selected as a treatment method for two patients based on the patients' characteristics. When only one gland is treated, the efficacy of PEIT was considered to be similar to that of MIRP.
ISSN:0753-3322
1950-6007