Loading…
Lifestyle Intervention of Hypocaloric Dieting and Walking Reduces Abdominal Obesity and Improves Coronary Heart Disease Risk Factors in Obese, Postmenopausal, African-American and Caucasian Women
Background. There are few empirical data to support the claim that weight loss improves coronary heart disease (CHD) risk factors in postmenopausal women; nor is it known if there are racial differences in changes of body fat distribution, lipids, glucose tolerance, and blood pressure with weight lo...
Saved in:
| Published in: | The journals of gerontology. Series A, Biological sciences and medical sciences Biological sciences and medical sciences, 2003-02, Vol.58 (2), p.M181-M189 |
|---|---|
| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c468t-b612d41325ff9dc3a96223ad32f57703a9f45718441d3016c61ae8ee9a8c008a3 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c468t-b612d41325ff9dc3a96223ad32f57703a9f45718441d3016c61ae8ee9a8c008a3 |
| container_end_page | M189 |
| container_issue | 2 |
| container_start_page | M181 |
| container_title | The journals of gerontology. Series A, Biological sciences and medical sciences |
| container_volume | 58 |
| creator | Nicklas, Barbara J. Dennis, Karen E. Berman, Dora M. Sorkin, John Ryan, Alice S. Goldberg, Andrew P. |
| description | Background. There are few empirical data to support the claim that weight loss improves coronary heart disease (CHD) risk factors in postmenopausal women; nor is it known if there are racial differences in changes of body fat distribution, lipids, glucose tolerance, and blood pressure with weight loss. This study determined the efficacy of a lifestyle weight loss intervention in reducing total and abdominal obesity and improving CHD risk factors in obese Caucasian and African-American postmenopausal women. Methods. Body composition (dual-energy x-ray absorptiometry), abdominal fat areas (computed tomography scan), lipoprotein lipids, insulin, glucose tolerance, and blood pressure were measured before and after 6 months of hypocaloric diet and low-intensity walking in 76 overweight or obese (body mass index > 25 kg/m2), Caucasian (72%) or African-American (28%), postmenopausal (age = 60 ± 5 years) women who completed the study. Results. Absolute amount of body weight lost was similar in Caucasians (−5.4 ± 3.6 kg) and African Americans (−3.9 ± 3.6 kg), but Caucasian women lost relatively more fat mass (p |
| doi_str_mv | 10.1093/gerona/58.2.M181 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_73030151</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>426544431</sourcerecordid><originalsourceid>FETCH-LOGICAL-c468t-b612d41325ff9dc3a96223ad32f57703a9f45718441d3016c61ae8ee9a8c008a3</originalsourceid><addsrcrecordid>eNpdkUtvEzEUhUcIREthzwpZLFh1Uj_iGc8ySmkTKaiolLbqxrrx3KnczNipPVOR38cfw3kIJLzxvfJ3ju17suwjoyNGK3H2iME7OJNqxEffmGKvsmNWSpVLIe9fp5qWVS4pLY6ydzE-0e2S_G12xLhUhZLqOPu9sA3GftMimbsewwu63npHfENmm7U30PpgDTm32Fv3SMDV5A7a1ba-xnowGMlkWfvOOmjJ1RKj7Tc7at6tg39Jx1O_fWPYkBlC6JNTRIhIrm1ckQswvQ-RWLfT4in57mPfofNrGCK0p2TSpOvB5ZMOd8XOewqDgWhTd-cT_D5700Ab8cNhP8l-Xny9mc7yxdXlfDpZ5GZcqD5fFozXYya4bJqqNgKqgnMBteCNLEua-mYsS6bGY1YLygpTMECFWIEylCoQJ9mXvW_62fOQpqY7Gw22LTj0Q9SloEknWQI__wc--SGkCUXNqSq44koliO4hE3yMARu9DrZLg9KM6m26ep-ulkpzvU03ST4dfIdlh_U_wSHOBOR7wMYef_09h7DSRSlKqWf3D5rfXv64vVEP-lz8AUWqtBs</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>208628288</pqid></control><display><type>article</type><title>Lifestyle Intervention of Hypocaloric Dieting and Walking Reduces Abdominal Obesity and Improves Coronary Heart Disease Risk Factors in Obese, Postmenopausal, African-American and Caucasian Women</title><source>Oxford Journals Online</source><creator>Nicklas, Barbara J. ; Dennis, Karen E. ; Berman, Dora M. ; Sorkin, John ; Ryan, Alice S. ; Goldberg, Andrew P.</creator><creatorcontrib>Nicklas, Barbara J. ; Dennis, Karen E. ; Berman, Dora M. ; Sorkin, John ; Ryan, Alice S. ; Goldberg, Andrew P.</creatorcontrib><description>Background. There are few empirical data to support the claim that weight loss improves coronary heart disease (CHD) risk factors in postmenopausal women; nor is it known if there are racial differences in changes of body fat distribution, lipids, glucose tolerance, and blood pressure with weight loss. This study determined the efficacy of a lifestyle weight loss intervention in reducing total and abdominal obesity and improving CHD risk factors in obese Caucasian and African-American postmenopausal women. Methods. Body composition (dual-energy x-ray absorptiometry), abdominal fat areas (computed tomography scan), lipoprotein lipids, insulin, glucose tolerance, and blood pressure were measured before and after 6 months of hypocaloric diet and low-intensity walking in 76 overweight or obese (body mass index > 25 kg/m2), Caucasian (72%) or African-American (28%), postmenopausal (age = 60 ± 5 years) women who completed the study. Results. Absolute amount of body weight lost was similar in Caucasians (−5.4 ± 3.6 kg) and African Americans (−3.9 ± 3.6 kg), but Caucasian women lost relatively more fat mass (p <.05). Both groups decreased their subcutaneous abdominal fat, and Caucasian women decreased their visceral fat area, but there were no racial differences in the magnitude of abdominal fat lost. The intervention decreased triglyceride and increased high-density lipoprotein and high-density lipoprotein 2 cholesterol in both races, and it decreased total and low-density lipoprotein cholesterol in Caucasian women (p <.05–.0001). Fasting glucose and glucose area during the oral glucose tolerance test decreased (p <.0001) in Caucasian women, whereas insulin area decreased in both Caucasian (p <.01) and African-American (p <.05) women. Blood pressure decreased the most in women with higher blood pressures at baseline. Changes in lipids, fasting glucose and insulin, their responses during the oral glucose tolerance test, and blood pressure were not different between racial groups. Conclusions. Weight loss achieved through a lifestyle intervention of energy restriction and increased physical activity is an equally effective therapy in African-American and Caucasian obese, postmenopausal women for improving glucose and lipid CHD risk factors.</description><identifier>ISSN: 1079-5006</identifier><identifier>EISSN: 1758-535X</identifier><identifier>DOI: 10.1093/gerona/58.2.M181</identifier><identifier>PMID: 12586858</identifier><language>eng</language><publisher>United States: Oxford University Press</publisher><subject>Abdomen ; Aged ; Anaerobic Threshold ; Black or African American ; Black People ; Blood Chemical Analysis ; Blood Glucose - analysis ; Blood Pressure Determination ; Body Composition - physiology ; Body Mass Index ; Cardiovascular disease ; Cohort Studies ; Coronary Disease - ethnology ; Coronary Disease - prevention & control ; Diet ; Diet, Reducing ; Energy Metabolism ; Exercise ; Female ; Follow-Up Studies ; Health risk assessment ; Humans ; Intervention ; Life Style ; Lifestyles ; Middle Aged ; Multivariate Analysis ; Obesity ; Obesity - ethnology ; Obesity - prevention & control ; Physical Fitness - physiology ; Postmenopause ; Probability ; Walking - physiology ; White People</subject><ispartof>The journals of gerontology. Series A, Biological sciences and medical sciences, 2003-02, Vol.58 (2), p.M181-M189</ispartof><rights>Copyright Gerontological Society of America, Incorporated Feb 2003</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c468t-b612d41325ff9dc3a96223ad32f57703a9f45718441d3016c61ae8ee9a8c008a3</citedby><cites>FETCH-LOGICAL-c468t-b612d41325ff9dc3a96223ad32f57703a9f45718441d3016c61ae8ee9a8c008a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12586858$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nicklas, Barbara J.</creatorcontrib><creatorcontrib>Dennis, Karen E.</creatorcontrib><creatorcontrib>Berman, Dora M.</creatorcontrib><creatorcontrib>Sorkin, John</creatorcontrib><creatorcontrib>Ryan, Alice S.</creatorcontrib><creatorcontrib>Goldberg, Andrew P.</creatorcontrib><title>Lifestyle Intervention of Hypocaloric Dieting and Walking Reduces Abdominal Obesity and Improves Coronary Heart Disease Risk Factors in Obese, Postmenopausal, African-American and Caucasian Women</title><title>The journals of gerontology. Series A, Biological sciences and medical sciences</title><addtitle>J Gerontol A Biol Sci Med Sci</addtitle><description>Background. There are few empirical data to support the claim that weight loss improves coronary heart disease (CHD) risk factors in postmenopausal women; nor is it known if there are racial differences in changes of body fat distribution, lipids, glucose tolerance, and blood pressure with weight loss. This study determined the efficacy of a lifestyle weight loss intervention in reducing total and abdominal obesity and improving CHD risk factors in obese Caucasian and African-American postmenopausal women. Methods. Body composition (dual-energy x-ray absorptiometry), abdominal fat areas (computed tomography scan), lipoprotein lipids, insulin, glucose tolerance, and blood pressure were measured before and after 6 months of hypocaloric diet and low-intensity walking in 76 overweight or obese (body mass index > 25 kg/m2), Caucasian (72%) or African-American (28%), postmenopausal (age = 60 ± 5 years) women who completed the study. Results. Absolute amount of body weight lost was similar in Caucasians (−5.4 ± 3.6 kg) and African Americans (−3.9 ± 3.6 kg), but Caucasian women lost relatively more fat mass (p <.05). Both groups decreased their subcutaneous abdominal fat, and Caucasian women decreased their visceral fat area, but there were no racial differences in the magnitude of abdominal fat lost. The intervention decreased triglyceride and increased high-density lipoprotein and high-density lipoprotein 2 cholesterol in both races, and it decreased total and low-density lipoprotein cholesterol in Caucasian women (p <.05–.0001). Fasting glucose and glucose area during the oral glucose tolerance test decreased (p <.0001) in Caucasian women, whereas insulin area decreased in both Caucasian (p <.01) and African-American (p <.05) women. Blood pressure decreased the most in women with higher blood pressures at baseline. Changes in lipids, fasting glucose and insulin, their responses during the oral glucose tolerance test, and blood pressure were not different between racial groups. Conclusions. Weight loss achieved through a lifestyle intervention of energy restriction and increased physical activity is an equally effective therapy in African-American and Caucasian obese, postmenopausal women for improving glucose and lipid CHD risk factors.</description><subject>Abdomen</subject><subject>Aged</subject><subject>Anaerobic Threshold</subject><subject>Black or African American</subject><subject>Black People</subject><subject>Blood Chemical Analysis</subject><subject>Blood Glucose - analysis</subject><subject>Blood Pressure Determination</subject><subject>Body Composition - physiology</subject><subject>Body Mass Index</subject><subject>Cardiovascular disease</subject><subject>Cohort Studies</subject><subject>Coronary Disease - ethnology</subject><subject>Coronary Disease - prevention & control</subject><subject>Diet</subject><subject>Diet, Reducing</subject><subject>Energy Metabolism</subject><subject>Exercise</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Health risk assessment</subject><subject>Humans</subject><subject>Intervention</subject><subject>Life Style</subject><subject>Lifestyles</subject><subject>Middle Aged</subject><subject>Multivariate Analysis</subject><subject>Obesity</subject><subject>Obesity - ethnology</subject><subject>Obesity - prevention & control</subject><subject>Physical Fitness - physiology</subject><subject>Postmenopause</subject><subject>Probability</subject><subject>Walking - physiology</subject><subject>White People</subject><issn>1079-5006</issn><issn>1758-535X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><recordid>eNpdkUtvEzEUhUcIREthzwpZLFh1Uj_iGc8ySmkTKaiolLbqxrrx3KnczNipPVOR38cfw3kIJLzxvfJ3ju17suwjoyNGK3H2iME7OJNqxEffmGKvsmNWSpVLIe9fp5qWVS4pLY6ydzE-0e2S_G12xLhUhZLqOPu9sA3GftMimbsewwu63npHfENmm7U30PpgDTm32Fv3SMDV5A7a1ba-xnowGMlkWfvOOmjJ1RKj7Tc7at6tg39Jx1O_fWPYkBlC6JNTRIhIrm1ckQswvQ-RWLfT4in57mPfofNrGCK0p2TSpOvB5ZMOd8XOewqDgWhTd-cT_D5700Ab8cNhP8l-Xny9mc7yxdXlfDpZ5GZcqD5fFozXYya4bJqqNgKqgnMBteCNLEua-mYsS6bGY1YLygpTMECFWIEylCoQJ9mXvW_62fOQpqY7Gw22LTj0Q9SloEknWQI__wc--SGkCUXNqSq44koliO4hE3yMARu9DrZLg9KM6m26ep-ulkpzvU03ST4dfIdlh_U_wSHOBOR7wMYef_09h7DSRSlKqWf3D5rfXv64vVEP-lz8AUWqtBs</recordid><startdate>200302</startdate><enddate>200302</enddate><creator>Nicklas, Barbara J.</creator><creator>Dennis, Karen E.</creator><creator>Berman, Dora M.</creator><creator>Sorkin, John</creator><creator>Ryan, Alice S.</creator><creator>Goldberg, Andrew P.</creator><general>Oxford University Press</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>200302</creationdate><title>Lifestyle Intervention of Hypocaloric Dieting and Walking Reduces Abdominal Obesity and Improves Coronary Heart Disease Risk Factors in Obese, Postmenopausal, African-American and Caucasian Women</title><author>Nicklas, Barbara J. ; Dennis, Karen E. ; Berman, Dora M. ; Sorkin, John ; Ryan, Alice S. ; Goldberg, Andrew P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c468t-b612d41325ff9dc3a96223ad32f57703a9f45718441d3016c61ae8ee9a8c008a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Abdomen</topic><topic>Aged</topic><topic>Anaerobic Threshold</topic><topic>Black or African American</topic><topic>Black People</topic><topic>Blood Chemical Analysis</topic><topic>Blood Glucose - analysis</topic><topic>Blood Pressure Determination</topic><topic>Body Composition - physiology</topic><topic>Body Mass Index</topic><topic>Cardiovascular disease</topic><topic>Cohort Studies</topic><topic>Coronary Disease - ethnology</topic><topic>Coronary Disease - prevention & control</topic><topic>Diet</topic><topic>Diet, Reducing</topic><topic>Energy Metabolism</topic><topic>Exercise</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Health risk assessment</topic><topic>Humans</topic><topic>Intervention</topic><topic>Life Style</topic><topic>Lifestyles</topic><topic>Middle Aged</topic><topic>Multivariate Analysis</topic><topic>Obesity</topic><topic>Obesity - ethnology</topic><topic>Obesity - prevention & control</topic><topic>Physical Fitness - physiology</topic><topic>Postmenopause</topic><topic>Probability</topic><topic>Walking - physiology</topic><topic>White People</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nicklas, Barbara J.</creatorcontrib><creatorcontrib>Dennis, Karen E.</creatorcontrib><creatorcontrib>Berman, Dora M.</creatorcontrib><creatorcontrib>Sorkin, John</creatorcontrib><creatorcontrib>Ryan, Alice S.</creatorcontrib><creatorcontrib>Goldberg, Andrew P.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>The journals of gerontology. Series A, Biological sciences and medical sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nicklas, Barbara J.</au><au>Dennis, Karen E.</au><au>Berman, Dora M.</au><au>Sorkin, John</au><au>Ryan, Alice S.</au><au>Goldberg, Andrew P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lifestyle Intervention of Hypocaloric Dieting and Walking Reduces Abdominal Obesity and Improves Coronary Heart Disease Risk Factors in Obese, Postmenopausal, African-American and Caucasian Women</atitle><jtitle>The journals of gerontology. Series A, Biological sciences and medical sciences</jtitle><addtitle>J Gerontol A Biol Sci Med Sci</addtitle><date>2003-02</date><risdate>2003</risdate><volume>58</volume><issue>2</issue><spage>M181</spage><epage>M189</epage><pages>M181-M189</pages><issn>1079-5006</issn><eissn>1758-535X</eissn><abstract>Background. There are few empirical data to support the claim that weight loss improves coronary heart disease (CHD) risk factors in postmenopausal women; nor is it known if there are racial differences in changes of body fat distribution, lipids, glucose tolerance, and blood pressure with weight loss. This study determined the efficacy of a lifestyle weight loss intervention in reducing total and abdominal obesity and improving CHD risk factors in obese Caucasian and African-American postmenopausal women. Methods. Body composition (dual-energy x-ray absorptiometry), abdominal fat areas (computed tomography scan), lipoprotein lipids, insulin, glucose tolerance, and blood pressure were measured before and after 6 months of hypocaloric diet and low-intensity walking in 76 overweight or obese (body mass index > 25 kg/m2), Caucasian (72%) or African-American (28%), postmenopausal (age = 60 ± 5 years) women who completed the study. Results. Absolute amount of body weight lost was similar in Caucasians (−5.4 ± 3.6 kg) and African Americans (−3.9 ± 3.6 kg), but Caucasian women lost relatively more fat mass (p <.05). Both groups decreased their subcutaneous abdominal fat, and Caucasian women decreased their visceral fat area, but there were no racial differences in the magnitude of abdominal fat lost. The intervention decreased triglyceride and increased high-density lipoprotein and high-density lipoprotein 2 cholesterol in both races, and it decreased total and low-density lipoprotein cholesterol in Caucasian women (p <.05–.0001). Fasting glucose and glucose area during the oral glucose tolerance test decreased (p <.0001) in Caucasian women, whereas insulin area decreased in both Caucasian (p <.01) and African-American (p <.05) women. Blood pressure decreased the most in women with higher blood pressures at baseline. Changes in lipids, fasting glucose and insulin, their responses during the oral glucose tolerance test, and blood pressure were not different between racial groups. Conclusions. Weight loss achieved through a lifestyle intervention of energy restriction and increased physical activity is an equally effective therapy in African-American and Caucasian obese, postmenopausal women for improving glucose and lipid CHD risk factors.</abstract><cop>United States</cop><pub>Oxford University Press</pub><pmid>12586858</pmid><doi>10.1093/gerona/58.2.M181</doi><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1079-5006 |
| ispartof | The journals of gerontology. Series A, Biological sciences and medical sciences, 2003-02, Vol.58 (2), p.M181-M189 |
| issn | 1079-5006 1758-535X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_73030151 |
| source | Oxford Journals Online |
| subjects | Abdomen Aged Anaerobic Threshold Black or African American Black People Blood Chemical Analysis Blood Glucose - analysis Blood Pressure Determination Body Composition - physiology Body Mass Index Cardiovascular disease Cohort Studies Coronary Disease - ethnology Coronary Disease - prevention & control Diet Diet, Reducing Energy Metabolism Exercise Female Follow-Up Studies Health risk assessment Humans Intervention Life Style Lifestyles Middle Aged Multivariate Analysis Obesity Obesity - ethnology Obesity - prevention & control Physical Fitness - physiology Postmenopause Probability Walking - physiology White People |
| title | Lifestyle Intervention of Hypocaloric Dieting and Walking Reduces Abdominal Obesity and Improves Coronary Heart Disease Risk Factors in Obese, Postmenopausal, African-American and Caucasian Women |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T23%3A30%3A59IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Lifestyle%20Intervention%20of%20Hypocaloric%20Dieting%20and%20Walking%20Reduces%20Abdominal%20Obesity%20and%20Improves%20Coronary%20Heart%20Disease%20Risk%20Factors%20in%20Obese,%20Postmenopausal,%20African-American%20and%20Caucasian%20Women&rft.jtitle=The%20journals%20of%20gerontology.%20Series%20A,%20Biological%20sciences%20and%20medical%20sciences&rft.au=Nicklas,%20Barbara%20J.&rft.date=2003-02&rft.volume=58&rft.issue=2&rft.spage=M181&rft.epage=M189&rft.pages=M181-M189&rft.issn=1079-5006&rft.eissn=1758-535X&rft_id=info:doi/10.1093/gerona/58.2.M181&rft_dat=%3Cproquest_cross%3E426544431%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c468t-b612d41325ff9dc3a96223ad32f57703a9f45718441d3016c61ae8ee9a8c008a3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=208628288&rft_id=info:pmid/12586858&rfr_iscdi=true |