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Inhibition of human pathogenic fungi by members of Zingiberaceae used by the Kenyah (Indonesian Borneo)
Extracts from 11 plant species belonging to the Zingiberaceae were tested for antifungal activity using disc diffusion bioassays. Extracts from several members, especially Alpinia galanga, Curcuma zedoaria and Zingiber purpureum, were found to have pronounced inhibitory activities against a wide var...
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Published in: | Journal of ethnopharmacology 2003-04, Vol.85 (2), p.289-293 |
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container_title | Journal of ethnopharmacology |
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creator | Ficker, Christine E Smith, Myron L Susiarti, Siti Leaman, Danna J Irawati, Ç Arnason, John T |
description | Extracts from 11 plant species belonging to the Zingiberaceae were tested for antifungal activity using disc diffusion bioassays. Extracts from several members, especially
Alpinia galanga,
Curcuma zedoaria and
Zingiber purpureum, were found to have pronounced inhibitory activities against a wide variety of human pathogenic fungi, including strains resistant to the common antifungals amphotericin B and ketoconazole. As members of the Zingiberaceae are generally regarded as safe for human consumption, these species are excellent candidates for development as novel therapeutics. |
doi_str_mv | 10.1016/S0378-8741(03)00009-6 |
format | article |
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Alpinia galanga,
Curcuma zedoaria and
Zingiber purpureum, were found to have pronounced inhibitory activities against a wide variety of human pathogenic fungi, including strains resistant to the common antifungals amphotericin B and ketoconazole. As members of the Zingiberaceae are generally regarded as safe for human consumption, these species are excellent candidates for development as novel therapeutics.</description><identifier>ISSN: 0378-8741</identifier><identifier>EISSN: 1872-7573</identifier><identifier>DOI: 10.1016/S0378-8741(03)00009-6</identifier><identifier>PMID: 12639754</identifier><identifier>CODEN: JOETD7</identifier><language>eng</language><publisher>Shannon: Elsevier Ireland Ltd</publisher><subject>Antifungal Agents - pharmacology ; Antifungal resistance ; Biological and medical sciences ; Borneo ; Borneo ethnobotany ; Drug Resistance, Fungal ; Ethnobotany ; Fungi - drug effects ; General pharmacology ; Ginger ; Humans ; Medical sciences ; Medicine, Traditional ; Microbial Sensitivity Tests ; Mycoses - microbiology ; Pathogenic fungi ; Pharmacognosy. Homeopathy. Health food ; Pharmacology. Drug treatments ; Plant Extracts - pharmacology ; Traditional phytomedicine ; Zingiberaceae ; Zingiberaceae - chemistry</subject><ispartof>Journal of ethnopharmacology, 2003-04, Vol.85 (2), p.289-293</ispartof><rights>2003 Elsevier Science Ireland Ltd</rights><rights>2003 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c457t-de0e56743f1c9687ccd229f818c23dd0a78242a620c9313e04b9546498a25b793</citedby><cites>FETCH-LOGICAL-c457t-de0e56743f1c9687ccd229f818c23dd0a78242a620c9313e04b9546498a25b793</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=14660157$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12639754$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ficker, Christine E</creatorcontrib><creatorcontrib>Smith, Myron L</creatorcontrib><creatorcontrib>Susiarti, Siti</creatorcontrib><creatorcontrib>Leaman, Danna J</creatorcontrib><creatorcontrib>Irawati, Ç</creatorcontrib><creatorcontrib>Arnason, John T</creatorcontrib><title>Inhibition of human pathogenic fungi by members of Zingiberaceae used by the Kenyah (Indonesian Borneo)</title><title>Journal of ethnopharmacology</title><addtitle>J Ethnopharmacol</addtitle><description>Extracts from 11 plant species belonging to the Zingiberaceae were tested for antifungal activity using disc diffusion bioassays. Extracts from several members, especially
Alpinia galanga,
Curcuma zedoaria and
Zingiber purpureum, were found to have pronounced inhibitory activities against a wide variety of human pathogenic fungi, including strains resistant to the common antifungals amphotericin B and ketoconazole. As members of the Zingiberaceae are generally regarded as safe for human consumption, these species are excellent candidates for development as novel therapeutics.</description><subject>Antifungal Agents - pharmacology</subject><subject>Antifungal resistance</subject><subject>Biological and medical sciences</subject><subject>Borneo</subject><subject>Borneo ethnobotany</subject><subject>Drug Resistance, Fungal</subject><subject>Ethnobotany</subject><subject>Fungi - drug effects</subject><subject>General pharmacology</subject><subject>Ginger</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Medicine, Traditional</subject><subject>Microbial Sensitivity Tests</subject><subject>Mycoses - microbiology</subject><subject>Pathogenic fungi</subject><subject>Pharmacognosy. Homeopathy. Health food</subject><subject>Pharmacology. 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Homeopathy. Health food</topic><topic>Pharmacology. 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Alpinia galanga,
Curcuma zedoaria and
Zingiber purpureum, were found to have pronounced inhibitory activities against a wide variety of human pathogenic fungi, including strains resistant to the common antifungals amphotericin B and ketoconazole. As members of the Zingiberaceae are generally regarded as safe for human consumption, these species are excellent candidates for development as novel therapeutics.</abstract><cop>Shannon</cop><pub>Elsevier Ireland Ltd</pub><pmid>12639754</pmid><doi>10.1016/S0378-8741(03)00009-6</doi><tpages>5</tpages></addata></record> |
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subjects | Antifungal Agents - pharmacology Antifungal resistance Biological and medical sciences Borneo Borneo ethnobotany Drug Resistance, Fungal Ethnobotany Fungi - drug effects General pharmacology Ginger Humans Medical sciences Medicine, Traditional Microbial Sensitivity Tests Mycoses - microbiology Pathogenic fungi Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Extracts - pharmacology Traditional phytomedicine Zingiberaceae Zingiberaceae - chemistry |
title | Inhibition of human pathogenic fungi by members of Zingiberaceae used by the Kenyah (Indonesian Borneo) |
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