The optimal duration and delay of first aid treatment for deep partial thickness burn injuries

• Published in: Burns 2010-08, Vol.36 (5), p.673-679
• Main Authors: Cuttle, Leila, Kempf, Margit, Liu, Pei-Yun, Kravchuk, Olena, Kimble, Roy M
• Format: Article
• Language: English
• Subjects: Animals; Biological and medical sciences; Biopsy; Body Temperature; Burn; Burns; Burns - pathology; Burns - therapy; Cicatrix - pathology; Cold; Critical Care; Cryotherapy - methods; Delay; Duration; Epithelium - pathology; First Aid; Granulation Tissue - pathology; Human viral diseases; Infectious diseases; Medical sciences; Partial thickness; Porcine model; Swine; Time Factors; Traumas. Diseases due to physical agents; Viral diseases; Viral diseases of the respiratory system and ent viral diseases; Water; Water - administration & dosage; Wound Healing - physiology
• ISSN: 0305-4179; 1879-1409
• DOI: 10.1016/j.burns.2009.08.002

Abstract Using our porcine model of deep dermal partial thickness burn injury, various durations (10 min, 20 min, 30 min or 1 h) and delays (immediate, 10 min, 1 h, 3 h) of 15 °C running water first aid were applied to burns and compared to untreated controls. The subdermal temperatures were monitored during the treatment and wounds observed weekly for 6 weeks, for re-epithelialisation, wound surface area and cosmetic appearance. At 6 weeks after the burn, tissue biopsies were taken of the scar for histological analysis. Results showed that immediate application of cold running water for 20 min duration is associated with an improvement in re-epithelialisation over the first 2 weeks post-burn and decreased scar tissue at 6 weeks. First aid application of cold water for as little as 10 min duration or up to 1 h delay still provides benefit.