Metabolic Evaluation in Stone Disease Metabolic Differences Between the Pediatric and Adult Patients With Stone Disease

Objective To determine the metabolic risk factors in children and adults with stone disease and any differences between the metabolic risk factors of children and adult patients with stone disease. Methods Between 1999 and 2007, 285 adults with recurrent stone disease and 71 children with primary or...

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Bibliographic Details
Published in:Urology (Ridgewood, N.J.) N.J.), 2010-07, Vol.76 (1), p.238-241
Main Authors: Karabacak, Osman Raif, Ipek, Bulent, Ozturk, Ufuk, Demirel, Fuat, Saltas, Hakan, Altug, Ugur
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age Factors
Aged
Biological and medical sciences
Child
Child, Preschool
Female
Humans
Infant
Male
Medical sciences
Middle Aged
Nephrology. Urinary tract diseases
Risk Factors
Urinary Calculi - epidemiology
Urinary Calculi - metabolism
Urology
Young Adult
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Summary:Objective To determine the metabolic risk factors in children and adults with stone disease and any differences between the metabolic risk factors of children and adult patients with stone disease. Methods Between 1999 and 2007, 285 adults with recurrent stone disease and 71 children with primary or recurrent urinary stone disease underwent metabolic evaluation in our clinic. The evaluation included blood chemistry studies and 24-hour urine collection in the pediatric and adult groups. Results The mean age of the children was 9.35 years (range: 1-14) and 42.1 years (range: 14-71) in the adult patients. Metabolic risk factors were demonstrated in 90.53% (n = 258) of the adult and 88.73% (n = 63) of the pediatric patients. Although hypercalciuria (50.5%, n = 144) was the most common metabolic risk factor in the adult group, hypocitraturia was the most common metabolic risk factor in the pediatric group (57.74%, n = 41). Furthermore, in the adult group, 136 patients had more than 1 risk factor, and in the pediatric group, 24 patients had more than 1 risk factor. Conclusion Although hypocitraturia is the most common risk factor in pediatric urolithiasis patients and hypercalciuria is the most common risk factor in adult patients, all patients with stone formation should be given a limited metabolic evaluation because such patients may also have a metabolic abnormality.
ISSN:0090-4295
1527-9995
DOI:10.1016/j.urology.2010.01.036