Outcome of anorectal malformations and Hirschsprung's disease beyond childhood

• Published in: Seminars in pediatric surgery 2010-05, Vol.19 (2), p.160-167
• Main Authors: Rintala, Risto J., MD, PhD, Pakarinen, Mikko P., MD, PhD
• Format: Article
• Language: English
• Subjects: Adult; Anal Canal - abnormalities; Anal Canal - surgery; Anorectal malformation; Child; Digestive System Abnormalities - surgery; Digestive System Surgical Procedures; Down Syndrome - complications; Fecal incontinence; Fecal Incontinence - epidemiology; Fecal Incontinence - psychology; Hirschsprung disease; Hirschsprung Disease - complications; Hirschsprung Disease - surgery; Humans; Imperforate anus; Pediatrics; Postoperative Complications - epidemiology; Recovery of Function; Rectum - abnormalities; Rectum - surgery; Surgery; Thyroid Neoplasms - complications; Treatment Outcome; Urinary Incontinence - complications; Urinary Tract - abnormalities
• ISSN: 1055-8586; 1532-9453
• DOI: 10.1053/j.sempedsurg.2009.11.021

Anorectal malformations (ARMs) and Hirschsprung disease (HD) are the most common congenital colorectal defects in the newborn. The outcomes of HD and ARMs have improved significantly because of improved understanding of the pathologic anatomy and physiology of these defects and of the modern surgical techniques. Still, many patients suffer from defective bowel control even as adults. Some of these also have problems with urinary control and sexual functions. The functional problems are more pronounced in patients with ARMs. Compared with healthy people, both patients with ARMs and those with HD have limitations in their quality of life. Inferior quality of life is more common in patients with ARMs. There are very few published data on long-term outcome of adults with ARMs and HD. The effect of aging on the functional outcome and quality of life remains unclear, although some preliminary data suggest that the bowel function and quality of life may deteriorate with aging.