Methicillin-Resistant Staphylococcus aureus in U.S. Hospitals, 1975-1991

Objectives: Analyze changes that have occurred among U.S. hospitals over a 17-year period, 1975 through 1991, in the percentage of Staphylococcus aureus resistant to β-lactam antibiotics and associated with nosocomial infections. Design: Retrospective review. The percentage of methicillin-resistant...

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Bibliographic Details
Published in:Infection control and hospital epidemiology 1992-10, Vol.13 (10), p.582-586
Main Authors: Panlilio, Adelisa L., Culver, David H., Gaynes, Robert P., Banerjee, Shailen, Henderson, Tonya S., Tolson, James S., Martone, William J.
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - pharmacology
Cross Infection - epidemiology
Cross Infection - microbiology
Epidemiology
Geographic regions
Geographical surveys
Hospital Bed Capacity
Hospital beds
Hospitals - classification
Hospitals - statistics & numerical data
Hospitals - trends
Humans
Infections
Lactams
Methicillin Resistance
Methicillin resistant staphylococcus aureus
Microbial Sensitivity Tests
Nursing
Psychiatric hospitals
Staphylococcal Infections - epidemiology
Staphylococcal Infections - microbiology
Staphylococcus
Staphylococcus aureus
Staphylococcus aureus - isolation & purification
Surveillance
United States - epidemiology
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Summary:Objectives: Analyze changes that have occurred among U.S. hospitals over a 17-year period, 1975 through 1991, in the percentage of Staphylococcus aureus resistant to β-lactam antibiotics and associated with nosocomial infections. Design: Retrospective review. The percentage of methicillin-resistant S aureus (MRSA) was defined as the number of S aureus isolates resistant to either methicillin, oxacillin, or nafcillin divided by the total number of S aureus isolates for which methicillin, oxacillin, or nafcillin susceptibility test results were reported to the National Nosocomial Infections Surveillance (NNIS) System. Setting: NNIS System hospitals. Results: Of the 66,132 S aureus isolates that were tested for susceptibility to methicillin, oxacillin, or nafcillin during 1975 through 1991, 6,986 (11%) were resistant to methicillin, oxacillin, or nafcillin. The percentage MRSA among all hospitals rose from 2.4% in 1975 to 29% in 1991, but the rate of increase differed significantly among 3 bed-size categories:
ISSN:0899-823X
1559-6834
DOI:10.1086/646432