Molecular Biology's Lessons about Toxoplasma Development: Stage-specific Homologs

Within intermediate hosts (such as humans), the protozoan parasite Toxoplasma gondii has two life cycle stages: a rapidly replicating form called a tachyzoite and a slowly growing, quiescent form called a bradyzoite. Recently, molecular biology studies have shown that tachyzoites and bradyzoites exp...

Full description

Saved in:
Bibliographic Details
Published in:Parasitology Today 1998-12, Vol.14 (12), p.490-493
Main Authors: Knoll, L.J., Boothroyd, J.C.
Format: Article
Language:English
Subjects:
Biochemistry. Physiology. Immunology. Molecular biology
Biological and medical sciences
bradyzoite
bradyzoites
differentiation
Fundamental and applied biological sciences. Psychology
gene expression
Protozoa
tachyzoite
tachyzoites
Toxoplasma
Toxoplasma gondii
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Within intermediate hosts (such as humans), the protozoan parasite Toxoplasma gondii has two life cycle stages: a rapidly replicating form called a tachyzoite and a slowly growing, quiescent form called a bradyzoite. Recently, molecular biology studies have shown that tachyzoites and bradyzoites express a number of homologs (ie. evolutionary related genes)expressed exclusively in one or the other stage. Here, Laura Knoll and John Boothroyd describe examples of how these stage-specific homologs were discovered, and speculate about their regulation and functional significance.
ISSN:0169-4758
1873-1473
DOI:10.1016/S0169-4758(98)01347-7