Review of magnetic resonance spectroscopy in the liver and the pancreas

Proton magnetic resonance spectroscopy is a powerful tool for in vivo biochemical characterization of normal and abnormal tissues. The initial application in the abdomen was the measurement of fat concentration in the liver using chemical shift imaging. The success of chemical shift imaging in provi...

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Bibliographic Details
Published in:Topics in magnetic resonance imaging 2009-04, Vol.20 (2), p.89-97
Main Authors: Perman, William H, Balci, Numan Cem, Akduman, Isin
Format: Article
Language:English
Subjects:
Biomarkers - analysis
Computer Simulation
Diagnosis, Computer-Assisted - methods
Humans
Lipids - analysis
Liver - metabolism
Liver Diseases - diagnosis
Liver Diseases - metabolism
Magnetic Resonance Spectroscopy - methods
Models, Biological
Pancreas - metabolism
Pancreatic Diseases - diagnosis
Pancreatic Diseases - metabolism
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Summary:Proton magnetic resonance spectroscopy is a powerful tool for in vivo biochemical characterization of normal and abnormal tissues. The initial application in the abdomen was the measurement of fat concentration in the liver using chemical shift imaging. The success of chemical shift imaging in providing a semiquantitative measure of liver fat concentration led to the application of the more quantitative single-voxel volume-selective spectroscopy of the liver. This single-voxel volume-selective spectroscopic technique is able to characterize the different lipids and metabolites present in the liver and the pancreas, providing information about the ratio of unsaturated and saturated lipids. The purposes of this article were to review the spectroscopic techniques and to discuss some of the clinical applications of these techniques in the abdomen.
ISSN:0899-3459
1536-1004
DOI:10.1097/RMR.0b013e3181c422f1