Treatment of localized periodontal disease in pregnancy does not reduce the occurrence of preterm birth: results from the Periodontal Infections and Prematurity Study (PIPS)

• Published in: American journal of obstetrics and gynecology 2010-02, Vol.202 (2), p.147.e1-147.e8
• Main Authors: Macones, George A., MD, Parry, Samuel, MD, Nelson, Deborah B., PhD, Strauss, Jerome F., MD, PhD, Ludmir, Jack, MD, Cohen, Arnold W., MD, Stamilio, David M., MD, Appleby, Dina, MS, Clothier, Bonnie, PhD, Sammel, Mary D., ScD, Jeffcoat, Marjorie, DMD
• Format: Article
• Language: English
• Subjects: Adult; Biological and medical sciences; Diseases of mother, fetus and pregnancy; Facial bones, jaws, teeth, parodontium: diseases, semeiology; Female; Gestational Age; Gynecology. Andrology. Obstetrics; Humans; Infant, Newborn; Medical sciences; Non tumoral diseases; Obstetrics and Gynecology; Otorhinolaryngology. Stomatology; periodontal disease; Periodontal Diseases - therapy; Pregnancy; Pregnancy Complications - therapy; Pregnancy. Fetus. Placenta; Premature Birth - prevention & control; spontaneous preterm delivery
• ISSN: 0002-9378; 1097-6868
• DOI: 10.1016/j.ajog.2009.10.892

Objective The purpose of this study was to test whether treating periodontal disease (PD) in pregnancy will reduce the incidence of spontaneous preterm delivery (SPTD) at ≤35 weeks of gestation. Study Design A multicenter, randomized clinical trial was performed. Subjects with PD were randomized to scaling and root planing (active) or tooth polishing (control). The primary outcome was the occurrence of SPTD at