Surgical treatment of prosthetic valve endocarditis in patients with double prostheses: is single-valve replacement safe?

• Published in: European journal of cardio-thoracic surgery 2010-01, Vol.37 (1), p.159-162
• Main Authors: Fernández Guerrero, Manuel L., Alonso, Julio, Rey, Manuel, Martinell, Jorge, Górgolas, Miguel, Artiz, Victor, Fraile, Julian
• Format: Article
• Language: English
• Subjects: Aged; Aortic Valve - diagnostic imaging; Aortic Valve - microbiology; Aortic Valve - surgery; Biological and medical sciences; Cardiology. Vascular system; Echocardiography, Transesophageal; Endocardial and cardiac valvular diseases; Endocarditis; Endocarditis, Bacterial - diagnostic imaging; Endocarditis, Bacterial - microbiology; Endocarditis, Bacterial - surgery; Female; Heart; Heart Valve Prosthesis - adverse effects; Heart Valve Prosthesis Implantation - adverse effects; Heart Valve Prosthesis Implantation - methods; Humans; Male; Medical sciences; Middle Aged; Mitral Valve - diagnostic imaging; Mitral Valve - microbiology; Mitral Valve - surgery; Pneumology; Prosthesis-Related Infections - diagnostic imaging; Prosthesis-Related Infections - microbiology; Prosthesis-Related Infections - surgery; Prosthetic valve endocarditis; Retrospective Studies; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the heart; Treatment Outcome; Valve replacement
• ISSN: 1010-7940; 1873-734X
• DOI: 10.1016/j.ejcts.2009.06.019

Objective: Bias against operating on patients with prosthetic valve endocarditis (PVE) who have multiple prostheses may preclude the use of life-saving valve replacement. We investigated the accuracy of the preoperative diagnosis of PVE in patients with both mitral and aortic prosthesis and the safety of single-valve replacement when only one valve seemed infected. Methods: Patients with a diagnosis of active PVE who had mitral and aortic prosthesis in place were assessed. We looked at the methods for diagnosis, causative agents, indication for valve replacement, operative findings and outcome. Results: Twenty patients, who had both mitral and aortic prostheses and a diagnosis of PVE, were assessed. Streptococci and staphylococci caused 70% of cases. By means of echocardiography, the valves involved were: mitral (11 patients), aortic (six patients), and in three cases both prosthetic valves seemed infected. Surgery was undertaken in 17 patients (85%). The positive predictive value of transesophageal echocardiogram (TEE) for the preoperative diagnosis of the site of infection was 100%. In 13 patients, only the prosthetic valve that seemed infected was replaced. Four of these patients died within a week after the procedure. Nine patients survived the surgical procedure, completed a course of antimicrobial therapy and were followed up for 15.78 months (95% CI: 12.83–18.72). All were considered cured and relapses were not observed. Conclusions: TEE allowed a diagnosis of site involvement that did correlate with the anatomic diagnosis obtained during the operation. This fact contributed to the management of patients and was of great help in guiding the surgical intervention. Echo-oriented single-valve replacement may be a safe strategy for patients with PVE and double prostheses.