Treatment and prognosis of early multiple gastric cancer

• Published in: European journal of surgical oncology 2003-08, Vol.29 (6), p.511-514
• Main Authors: Borie, F, Plaisant, N, Millat, B, Hay, J.M, Fagniez, P.L, De Saxce, B
• Format: Article
• Language: English
• Subjects: Adult; Aged; Biological and medical sciences; early gastric cancer; early multiple gastric cancer; Female; Gastrectomy - methods; Gastroenterology. Liver. Pancreas. Abdomen; Humans; Lymphatic Metastasis; Male; Medical sciences; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local - etiology; Neoplasms, Multiple Primary - diagnosis; Neoplasms, Multiple Primary - epidemiology; Neoplasms, Multiple Primary - pathology; Neoplasms, Multiple Primary - surgery; Prevalence; Prognosis; Proportional Hazards Models; Retrospective Studies; Stomach Neoplasms - diagnosis; Stomach Neoplasms - epidemiology; Stomach Neoplasms - pathology; Stomach Neoplasms - surgery; Stomach, duodenum, intestine, rectum, anus; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus; surgery; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the digestive system; Survival Analysis; Treatment Outcome; Tumors
• ISSN: 0748-7983; 1532-2157
• DOI: 10.1016/S0748-7983(03)00094-5

Aim: Early gastric cancer (EGC) may have a 5-year survival rate of over 90% following surgery. Early multifocal gastric cancer (EMGC) accounts for between 8.3 and 17% of all EGCs. A multicenter retrospective study is reported of prevalence, characteristics, prognosis and type of resection for EMGC patients. Method: 333 patients with EGC were operated on, between January 1979 and December 1988, and followed to June 1996. Results: 33 EGC patients had EMGC. There was no significant difference in clinico-pathological features between EGC and EMGC. 21 cases of EMGC underwent a subtotal gastrectomy and 12 underwent a total gastrectomy. Recurrences after subtotal gastrectomy were, respectively, 10 and 18% for EGC and EMGC patients (p=0.2). The cumulative 5 years specific survival rate for 298 EGC and 34 EMGC were 94 and 90%, respectively (p=0.9). Five-year survival rates after subtotal gastrectomy were 92 and 90% for EGC and EMGC patients, respectively (p=0.8). Conclusion: EGC and EMGC had the same clinico-pathological features and prognosis. A careful follow up of the stomach remnant is essential.