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Asymptomatic Infection with Borrelia burgdorferi

The natural history of asymptomatic seroconversion to Borrelia burgdorferi has been unclear. We report here, on the basis of a post hoc assessment, the frequency and outcome of asymptomatic seroconversion to B. burgdorferi in participants of a large Lyme disease vaccine trial. We show that infection...

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Published in:	Clinical infectious diseases 2003-08, Vol.37 (4), p.528-532
Main Authors:	Steere, Allen C., Sikand, Vijay K., Schoen, Robert T., Nowakowski, John
Format:	Article
Language:	English
Subjects:	Adolescent Adult Aged Antibodies Asymptomatic infections Bacterial diseases Biological and medical sciences Borrelia burgdorferi Borrelia burgdorferi - immunology Borrelia infections Double-Blind Method Enzyme linked immunosorbent assay Erythema Female Human bacterial diseases Humans Infections Infectious diseases Lyme disease Lyme Disease - epidemiology Lyme Disease - immunology Lyme Disease - physiopathology Lyme Disease - prevention & control Lyme Disease Vaccines - administration & dosage Lyme Disease Vaccines - adverse effects Lyme Disease Vaccines - immunology Major Articles Male Medical sciences Middle Aged Prevalence Statistical median Symptoms Treatment Outcome Tropical bacterial diseases Vaccination
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creator	Steere, Allen C. Sikand, Vijay K. Schoen, Robert T. Nowakowski, John
description	The natural history of asymptomatic seroconversion to Borrelia burgdorferi has been unclear. We report here, on the basis of a post hoc assessment, the frequency and outcome of asymptomatic seroconversion to B. burgdorferi in participants of a large Lyme disease vaccine trial. We show that infection with B. burgdorferi may be asymptomatic but that asymptomatic infection is unusual in the United States.
doi_str_mv	10.1086/376914
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source	JSTOR Archival Journals and Primary Sources Collection; Oxford Journals Online
subjects	Adolescent Adult Aged Antibodies Asymptomatic infections Bacterial diseases Biological and medical sciences Borrelia burgdorferi Borrelia burgdorferi - immunology Borrelia infections Double-Blind Method Enzyme linked immunosorbent assay Erythema Female Human bacterial diseases Humans Infections Infectious diseases Lyme disease Lyme Disease - epidemiology Lyme Disease - immunology Lyme Disease - physiopathology Lyme Disease - prevention & control Lyme Disease Vaccines - administration & dosage Lyme Disease Vaccines - adverse effects Lyme Disease Vaccines - immunology Major Articles Male Medical sciences Middle Aged Prevalence Statistical median Symptoms Treatment Outcome Tropical bacterial diseases Vaccination
title	Asymptomatic Infection with Borrelia burgdorferi
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