Different impact of biomarkers as mortality predictors among diabetic and nondiabetic patients undergoing hemodialysis

Diabetic patients undergoing hemodialysis demonstrate much worse survival rates than do nondiabetic patients undergoing hemodialysis. To search for risk predictors, a prospective cohort study was performed with 245 hemodialysis patients, including 84 with diabetes mellitus, for 2 yr. C-reactive prot...

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Bibliographic Details
Published in:Journal of the American Society of Nephrology 2003-09, Vol.14 (9), p.2329-2337
Main Authors: HOCHER, Berthold, ZIEBIG, Reinhard, ALTERMANN, Claudia, KRAUSE, Rolfdieter, ASMUS, Gernot, RICHTER, Claus-Michael, SLOWINSKI, Torsten, SINHA, Pranav, NEUMAYER, Hans-H
Format: Article
Language:English
Subjects:
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Apolipoproteins - blood
Biological and medical sciences
Biomarkers - blood
Blood Proteins - metabolism
Cholesterol - blood
Cohort Studies
Creatinine - blood
Diabetes Complications
Diabetes Mellitus - blood
Diabetes Mellitus - mortality
Emergency and intensive care: renal failure. Dialysis management
Humans
Intensive care medicine
Kidney Failure, Chronic - blood
Kidney Failure, Chronic - mortality
Kidney Failure, Chronic - therapy
Medical sciences
Predictive Value of Tests
Prospective Studies
Renal Dialysis
Risk Factors
Survival Rate
Triglycerides - blood
Troponin T - blood
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Summary:Diabetic patients undergoing hemodialysis demonstrate much worse survival rates than do nondiabetic patients undergoing hemodialysis. To search for risk predictors, a prospective cohort study was performed with 245 hemodialysis patients, including 84 with diabetes mellitus, for 2 yr. C-reactive protein, troponin T (TnT), total, HDL, LDL, and lipoprotein(a) cholesterol, apoA2, apoB, triglyceride, fibrinogen, D-dimer, albumin, and creatinine levels and clinical characteristics at the time of entry were recorded. Survival rates were compared with Kaplan-Meier and Cox regression analyses. Forty-three diabetic patients and 30 nondiabetic patients died. Among diabetic patients, oliguria (
ISSN:1046-6673
1533-3450
DOI:10.1097/01.ASN.0000081662.64171.9B