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Interactions between Mycobacterium tuberculosis and host cells: are mycobacterial sugars the key?
Mycobacterium tuberculosis has evolved successful strategies to invade and persist within macrophages. Intimate pathogen–macrophage contacts dictate receptor choice and probably specify the intracellular fate of these microrganisms. Binding to specific receptors, such as complement receptor type 3,...
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Published in: | Trends in microbiology (Regular ed.) 1998-08, Vol.6 (8), p.328-335 |
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container_end_page | 335 |
container_issue | 8 |
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container_title | Trends in microbiology (Regular ed.) |
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creator | Ehlers, Mario R.W Daffé, Mamadou |
description | Mycobacterium tuberculosis has evolved successful strategies to invade and persist within macrophages. Intimate pathogen–macrophage contacts dictate receptor choice and probably specify the intracellular fate of these microrganisms. Binding to specific receptors, such as complement receptor type 3, could provide an advantage. These interactions appear to involve surface polysaccharides and glycolipids. |
doi_str_mv | 10.1016/S0966-842X(98)01301-8 |
format | article |
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source | ScienceDirect Journals |
subjects | Animals capsule Carbohydrate Metabolism CR3 Humans macrophage Macrophage-1 Antigen - metabolism Mannose - metabolism MBP Mycobacterium Mycobacterium tuberculosis Mycobacterium tuberculosis - metabolism Mycobacterium tuberculosis - physiology PIM Receptors, Cell Surface - metabolism |
title | Interactions between Mycobacterium tuberculosis and host cells: are mycobacterial sugars the key? |
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