Microporous membrane blood oxygenators

Extracorporeal blood oxygenators are used to oxygenate blood during open‐heart surgery. Hydrophobic microporous flat‐sheet or hollow‐fiber membranes are used to separate blood and gas phases. Oxygen diffuses from the gas phase through the gas‐filled membrane pores into the blood. Mass‐transfer and f...

Full description

Saved in:
Bibliographic Details
Published in:AIChE journal 2005-02, Vol.51 (2), p.656-670
Main Authors: Wickramasinghe, S. R., Han, B., Garcia, J. D., Specht, R.
Format: Article
Language:English
Subjects:
Applied sciences
Blood
blood oxygenators
Chemical engineering
Diffusion
Exact sciences and technology
friction factor
Heat and mass transfer. Packings, plates
Hollow fiber membranes
mass transfer
microporous membranes
Oxygen
Oxygen transfer
Oxygenation
Surgery
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Extracorporeal blood oxygenators are used to oxygenate blood during open‐heart surgery. Hydrophobic microporous flat‐sheet or hollow‐fiber membranes are used to separate blood and gas phases. Oxygen diffuses from the gas phase through the gas‐filled membrane pores into the blood. Mass‐transfer and friction‐factor correlations have been developed for flat‐sheet and hollow‐fiber blood oxygenators. Generalized Graetz, Reynolds, and Schmidt numbers are used in these correlations to account for the shear‐thinning behavior of blood. Because oxygen not only dissolves in plasma but also binds to hemoglobin, a mass‐transfer enhancement factor based on film theory has been developed to account for oxygen binding to hemoglobin. Experimental results for oxygen transfer to bovine blood and both non‐Newtonian and Newtonian blood analogue fluids indicate that the correlations developed may be used to predict the performance of a blood oxygenator based on results for an experimentally simple system such as the oxygenation of deionized water. © 2005 American Institute of Chemical Engineers AIChE J, 51: 656–670, 2005
ISSN:0001-1541
1547-5905
DOI:10.1002/aic.10327