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Cost-effectiveness of positron emission tomography in breast cancer
In this study, we used quantitative decision tree modeling to assess the cost-effectiveness of a positron emission tomography (PET)-based management scenario for breast cancer in Canada. Two patient management scenarios were compared (with and without PET). A metaanalysis of studies for the accuracy...
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Published in: | Molecular imaging and biology 2005-09, Vol.7 (5), p.351-360 |
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Main Authors: | , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | In this study, we used quantitative decision tree modeling to assess the cost-effectiveness of a positron emission tomography (PET)-based management scenario for breast cancer in Canada.
Two patient management scenarios were compared (with and without PET). A metaanalysis of studies for the accuracy of PET in staging breast cancer was conducted. Life expectancies were calculated. Management costs were determined from previous cost-effective analyses, management costs from our institutions, and recently published Canadian cost estimates of various procedures.
A cost savings of $695 per person is expected for the PET strategy, with an increase in life expectancy (7.4 days), when compared with the non-PET strategy. This cost savings remained in favor of the PET strategy when subjected to a sensitivity analysis.
The use of a PET management strategy for the staging of breast cancer is expected to remain economically viable in Canada under various economic conditions. |
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ISSN: | 1536-1632 1860-2002 |
DOI: | 10.1007/s11307-005-0012-5 |