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Cost-effectiveness of positron emission tomography in breast cancer

In this study, we used quantitative decision tree modeling to assess the cost-effectiveness of a positron emission tomography (PET)-based management scenario for breast cancer in Canada. Two patient management scenarios were compared (with and without PET). A metaanalysis of studies for the accuracy...

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Bibliographic Details
Published in:Molecular imaging and biology 2005-09, Vol.7 (5), p.351-360
Main Authors: Sloka, J Scott, Hollett, Peter D, Mathews, Maria
Format: Article
Language:English
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Summary:In this study, we used quantitative decision tree modeling to assess the cost-effectiveness of a positron emission tomography (PET)-based management scenario for breast cancer in Canada. Two patient management scenarios were compared (with and without PET). A metaanalysis of studies for the accuracy of PET in staging breast cancer was conducted. Life expectancies were calculated. Management costs were determined from previous cost-effective analyses, management costs from our institutions, and recently published Canadian cost estimates of various procedures. A cost savings of $695 per person is expected for the PET strategy, with an increase in life expectancy (7.4 days), when compared with the non-PET strategy. This cost savings remained in favor of the PET strategy when subjected to a sensitivity analysis. The use of a PET management strategy for the staging of breast cancer is expected to remain economically viable in Canada under various economic conditions.
ISSN:1536-1632
1860-2002
DOI:10.1007/s11307-005-0012-5