Multislice spiral CT angiography in peripheral arterial occlusive disease: a valuable tool in detecting significant arterial lumen narrowing?

The aim of this study was to evaluate the potential of multislice CT angiography (CTA) in detecting hemodynamically significant (> or =70%) lesions of lower extremity inflow and runoff arteries. Fifty patients (42 men, 8 women; mean age 68 years) with peripheral arterial occlusive disease underwe...

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Bibliographic Details
Published in:European radiology 2004-09, Vol.14 (9), p.1681-1687
Main Authors: Portugaller, Horst R, Schoellnast, Helmut, Hausegger, Klaus A, Tiesenhausen, Kurt, Amann, Wilfried, Berghold, Andrea
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Angiography, Digital Subtraction
Arterial Occlusive Diseases - diagnostic imaging
Arteriosclerosis - diagnostic imaging
Female
Humans
Image Processing, Computer-Assisted
Ischemia - diagnostic imaging
Leg - blood supply
Male
Medical imaging
Middle Aged
Prospective Studies
Sensitivity and Specificity
Studies
Tomography, Spiral Computed
Veins & arteries
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Summary:The aim of this study was to evaluate the potential of multislice CT angiography (CTA) in detecting hemodynamically significant (> or =70%) lesions of lower extremity inflow and runoff arteries. Fifty patients (42 men, 8 women; mean age 68 years) with peripheral arterial occlusive disease underwent multislice spiral CTA and digital subtraction angiography (DSA) from the infrarenal aorta to the supramalleolar region. CT parameters were 4x2.5-mm collimation, 15-mm table increment/rotation (pitch 6), and 1.25-mm reconstruction increment. Semitransparent volume rendering technique (STVR) images with semitransparent display of the arterial lumen (opacity: 50%) and vascular calcifications (opacity: 20%), as well as maximum intensity projection (MIP), and MIP together with axial CT studies were independently reviewed for hemodynamically significant lesions (> or =70% cross-sectional area reduction). DSA was the standard of reference. In 46 patients, 260 lesions were found (95 stenoses, 165 occlusions). For detecting > or =70% lesions in all vessel regions, sensitivity and specificity were 84% and 78% (STVR), 89% and 74% (MIP), and 92% and 83% (MIP+axial CT), respectively, with a significantly lower sensitivity of STVR ( p
ISSN:0938-7994
1432-1084
DOI:10.1007/s00330-004-2289-1