Bone Mineral Density and Nutritional Profile in Morbidly Obese Women

• Published in: Obesity surgery 2010-10, Vol.20 (10), p.1372-1379
• Main Authors: Casagrande, Daniela Schaan, Repetto, Giuseppe, Mottin, Claudio Corá, Schneider, Rodolfo, Rizzolli, Jacqueline, Moretto, Myriam, Padoin, Alexandre Vontobel, Schaan, Beatriz D’Agord
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Allied Care; Bone Density; Cross-Sectional Studies; Female; Humans; Medicine; Medicine & Public Health; Middle Aged; Nutrition; Nutritional Status; Obesity; Obesity, Morbid - physiopathology; Parathyroid Hormone - blood; Prospective Studies; Surgery; Women; Young Adult
• ISSN: 0960-8923; 1708-0428
• DOI: 10.1007/s11695-010-0121-3

Background Morbid obesity may be associated with malnutrition. Because it is important to assess the preoperative nutritional/metabolic status and bone mineral density of these patients, this study was designed aiming to evaluate bone metabolism/mineral density and nutritional profile in morbidly obese women. Methods Thirty-three morbidly obese women in preoperative care for obesity surgery were enrolled. Blood samples were drawn to determine nutritional and metabolic status, and dual-energy X-ray absorptiometry (DXA) was performed to evaluate bone mineral density; 24-h recall and food frequency questionnaire (FFQ) were also evaluated. Results Twenty-seven (81.8%) women were premenopausal and six (18.2%) were postmenopausal. The mean body mass index was 43.2 ± 4.8 kg/m 2 , and 91% were Caucasian. Insulin-resistant subjects comprised 81.8% of the sample. The median (25–75 percentile) of the total intake of 24-h recall was 3,081 (2,718–3,737) and for FFQ 2,685 (2,284–4,400) calories. FFQ underestimated total energy value intake. The median of calcium was higher when evaluated by the FFQ as compared with the 24-h recall. Protein and lipid intakes were lower if evaluated by the FFQ as compared to the 24-h recall. Vitamin D levels were low in 18 (81.8%) patients. In one premenopausal woman, bone mineral density was low in the lumbar spine (L1–L4), and in one postmenopausal woman it was low in L1–L4, femoral neck and 1/3 proximal radius. Conclusions In this study, the nutritional status of morbidly obese women was good, except for markers of bone metabolism, with no detectable differences between pre- and postmenopausal women.