Steroids and varicella

Reasons for adverse outcomes of infectious diseases are always under scrutiny. We expect infectious illnesses to have a specific course and outcome. Outcomes outside of the expected range are unacceptable, although the natural course of each infection includes them. Adverse outcomes that are product...

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Bibliographic Details
Published in:Pediatrics (Evanston) 1993-08, Vol.92 (2), p.288-289
Main Authors: REICHES, N. A, JONES, J. F
Format: Article
Language:English
Subjects:
Adrenal Cortex Hormones - adverse effects
Adrenocortical hormones
Biological and medical sciences
Causes of
Chickenpox
Chickenpox - complications
Chickenpox - physiopathology
Child
Complications and side effects
Human viral diseases
Humans
Infections
Infectious diseases
Medical sciences
Pediatrics
Research Design
Steroids
Viral diseases
Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye
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Summary:Reasons for adverse outcomes of infectious diseases are always under scrutiny. We expect infectious illnesses to have a specific course and outcome. Outcomes outside of the expected range are unacceptable, although the natural course of each infection includes them. Adverse outcomes that are products of medical invention are of particular import because they imply changes inpractice. One such situation is corticosteroid-induced fatal or severe varicella-zoster virus (VZV) infections. This topic, although not new, has received considerable interest because of recent warnings by the Food and Drug Administration.1 Case reports, retrospective studies, and reviews that have appeared since the 1950s suggest that high-dose (
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.92.2.288