Primary vesicoureteral reflux in infants with a dilated fetal urinary tract

Vesicoureteral reflux (VUR) was recognized neonatally by voiding cystography in 25 of 117 infants with a dilated fetal urinary tract. There was a male preponderance (76%) and a high percentage (40%) of associated urinary malformations. Thirty-nine refluxing units were studied. All grades of VUR were...

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Bibliographic Details
Published in:European journal of pediatrics 1993-06, Vol.152 (6), p.523-525
Main Authors: RING, E, PETRITSCH, P, RICCABONA, M, HAIM-KUTTNIG, M, VILITS, P, RAUCHENWALD, M, FUEGER, G
Format: Article
Language:English
Subjects:
Biological and medical sciences
Cystostomy
Dilatation, Pathologic
Female
Fetal Diseases - diagnosis
Fetal Diseases - etiology
Follow-Up Studies
Humans
Infant, Newborn
Male
Malformations of the urinary system
Medical sciences
Nephrology. Urinary tract diseases
Pregnancy
Prenatal Diagnosis
Treatment Outcome
Ureterostomy
Urinary Diversion
Urinary Tract - abnormalities
Urinary tract. Prostate gland
Urography
Vesico-Ureteral Reflux - diagnosis
Vesico-Ureteral Reflux - etiology
Vesico-Ureteral Reflux - therapy
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Summary:Vesicoureteral reflux (VUR) was recognized neonatally by voiding cystography in 25 of 117 infants with a dilated fetal urinary tract. There was a male preponderance (76%) and a high percentage (40%) of associated urinary malformations. Thirty-nine refluxing units were studied. All grades of VUR were detected but gross dilating VUR dominated (59%). Spontaneous resolution was excellent in lower grades of VUR but was poor in gross VUR. Surgery was successfully performed in 13 renal units of nine patients with gross reflux, additional ipsilateral malformations, or pyelonephritis during antibiotic prophylaxis. Segmental renal scars developed in four kidneys after urinary infections, and a diffuse parenchymal lesion was noted in nine kidneys even at birth. One boy with duplication had a non-functioning refluxing system. Our results in a small number of infants show differences to children with VUR detected after urinary infections and seem to support the existence of a congenital reflux nephropathy.
ISSN:0340-6199
1432-1076
DOI:10.1007/BF01955065